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National Core Study - Data and Connectivity: COVID-19 Vaccines Pharmacovigilance (DaC-VaP)
Safe People
University of Oxford, Queen's University Belfast
Academic Institute
Eleftheria VasileiouAziz SheikhJoshua WicksDr Declan Bradley
Health Data Research UKUK Research and InnovationOffice for National Statistics
Safe Projects
36367500000000000
The aim of this study is to assess the safety, effectiveness and uptake of the currently licenced COVID-19 vaccines (Pfizer-BioNTech, Oxford-AstraZeneca and Moderna) in the UK. To do this, we will use anonymised individual level data routinely collected at primary, secondary, linked with mortality, laboratory and vaccination data across the UK. Unique national datasets will be developed and hosted within a Trusted Research Environment (TRE) in each UK nation with standardised individual-level analyses run across datasets. Pooled estimates across the UK national will also be provided. Specifically, our objectives are to: a) assess any vaccine related adverse events; b) assess vaccine effectiveness (VE) including household transmission; and c) measure variation in vaccine uptake
Safe Data
Anonymous
Not applicable
Not applicable
Not applicable
Recurring
Safe Setting
TRE