HDR Gateway logo
HDR Gateway logo

Bookmarks

National Core Study - Data and Connectivity: COVID-19 Vaccines Pharmacovigilance (DaC-VaP)

Safe People

Organisation name

University of Oxford, Queen's University Belfast

Organisation sector

Academic Institute

Applicant name(s)

Eleftheria VasileiouAziz SheikhJoshua WicksDr Declan Bradley

Funders/ Sponsors

Health Data Research UKUK Research and InnovationOffice for National Statistics

Safe Projects

Project ID

36367500000000000

Lay summary

The aim of this study is to assess the safety, effectiveness and uptake of the currently licenced COVID-19 vaccines (Pfizer-BioNTech, Oxford-AstraZeneca and Moderna) in the UK. To do this, we will use anonymised individual level data routinely collected at primary, secondary, linked with mortality, laboratory and vaccination data across the UK. Unique national datasets will be developed and hosted within a Trusted Research Environment (TRE) in each UK nation with standardised individual-level analyses run across datasets. Pooled estimates across the UK national will also be provided. Specifically, our objectives are to: a) assess any vaccine related adverse events; b) assess vaccine effectiveness (VE) including household transmission; and c) measure variation in vaccine uptake

Safe Data

Data sensitivity level

Anonymous

Legal basis for provision of data under Article 6

Not applicable

Common Law Duty of Confidentiality

Not applicable

National data opt-out applied?

Not applicable

Request frequency

Recurring

Safe Setting

Access type

TRE