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Genetic variation in colitis-associated colon cancer

Safe People

Organisation name

University College London

Organisation ID

grid.83440.3b

Applicant name(s)

Adam Levine

Safe Projects

Project ID

DAA080

Lay summary

Patients with inflammatory bowel disease (IBD) are at an increased risk of developing colorectal cancer. It is unknown whether IBD patients that develop colitis-associated colorectal cancer have an increased burden of genetic risk variants associated with sporadic colorectal cancer which may contribute to their likelihood of developing the disease. This project aims to calculate and examine genetic risk scores for colorectal cancer in IBD patients with colitis-associated colorectal cancer compared to IBD patients without cancer, patients with sporadic colorectal cancer and healthy controls.

Request category type

Research

Other approval committees

NIHR BioResource Data Access Committee

Latest approval date

29/07/2021

Safe Data

Dataset(s) name
Data sensitivity level

De-Personalised

Legal basis for provision of data under Article 6

(e) processing is necessary for the performance of a task carried out in the public interest or in the exercise of official authority vested in the controller;

Lawful conditions for provision of data under Article 9

(j) processing is necessary for archiving purposes in the public interest, scientific or historical research purposes or statistical purposes in accordance with Article 89(1) based on Union or Member State law which shall be proportionate to the aim pursued, respect the essence of the right to data protection and provide for suitable and specific measures to safeguard the fundamental rights and the interests of the data subject.

Common Law Duty of Confidentiality

The individual to whom the information relates has consented

National data opt-out applied?

No

Request frequency

One-off

Safe Setting

Access type

Release