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Histo-Mol GBM Collaborative (2021) Dataset

Population Size

1,857

People

Population Size statistic card

Years

2021 - 2021

Years statistic card

Associated BioSamples

None/not available

Associated BioSamples statistic card

Geographic coverage

United Kingdom

Republic of Ireland

...see more

Geographic coverage statistic card

Lead time

Variable

Lead time statistic card

Summary

Glioblastoma is the most aggressive type of brain tumour, with around 2,000 people diagnosed each year in the UK. In 2021, the diagnostic classification changed to include genetic and molecular features alongside histological criteria. This dataset of provides up-to-date information about >1850 pathologically confirmed glioblastoma patients diagnosed in a single year (2021) according to the WHO 2021 classification from 52 centres using a retrospective international cohort study design.

Documentation

The Histo-Mol GBM Collaborative (2021) dataset is an international retrospective multi-centre cohort study of pathologically confirmed glioblastoma patients diagnosed during a 1-year time-period.

This dataset contains data from the majority of United Kingdom Neuro-oncology centres (44/49), every neuro-oncology centre in New Zealand (5/5) and the Republic of Ireland (2/2), plus 1 centre from Australia.

This dataset provides a national level overview of pathologically confirmed glioblastoma patients diagnosed between 01/01/2021 and 31/12/2021 with granular individual patient data comprising demographics, presenting symptoms, tumour characteristics, full treatment characteristics, post-treatment surveillance details, recurrence information including treatment at all recurrences, and survival data.

Dataset type

Health and disease, Treatments/Interventions, Imaging types, Measurements/Tests

Dataset population size

1857

Keywords

Observations

Observed Node

Disambiguating Description

Measured Value

Measured Property

Observation Date

Events

Number of people who have died

1614

Overall Survival

14 May 2025

Persons

Number of individuals in the dataset

1857

Count

07 Sep 2025

Provenance

Purpose of dataset collection

Research cohort

Source of data extraction

Paper-based, EPR

Collection source setting

Secondary care - Outpatients, Secondary care - In-patients

Patient pathway description

Retrospective dataset covering the secondary care patient pathway for glioblastoma patients. Data collected from the neurosurgical and/or neuro-oncology centre.

Image contrast

Not stated

Biological sample availability

None/not available

Structural Metadata

Details

Publishing frequency

Static

Version

1.0.0

Modified

08/09/2025

Distribution release date

07/09/2025

Citation Requirements

On behalf of the Histo-Mol GBM Collaborative

Coverage

Start date

01/01/2021

End date

31/12/2021

Time lag

Not applicable

Geographic coverage

United Kingdom, Republic of Ireland, New Zealand, Australia

Minimum age range

18

Maximum age range

90

Follow-up

1 - 10 Years

Accessibility

Language

en

Alignment with standardised data models

LOCAL

Controlled vocabulary

LOCAL

Format

Excel

Data Access Request

Dataset pipeline status

Available

Access rights

In Progress

Time to dataset access

Variable

Access request cost

None

Access method category

TRE/SDE

Access service description

No direct access to the raw data is available due to data protection requirements. Summary data and targeted analysis can be provided through development of a collaboration with the project lead.

Jurisdiction

UK

Data use limitation

General research use

Data use requirements

Collaboration required

Data Controller

Dr Stephen Robinson on behalf of the Histo-Mol GBM Collaborative

Data Processor

Histo-Mol GBM Collaborative

Demographics

Dataset Types: Health and disease, Treatments/Interventions, Imaging types, Measurements/Tests

Dataset Sub-types: Cancer, Therapeutic, MRI,Pathology, Other diagnostics

Collection Sources: Secondary care - Outpatients, Secondary care - In-patients