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Cardio-Pulmonary Exercise Test (CPET) parameters in Adult Congenital Heart Disease (ACHD)

Population Size

Not reported
Population Size statistic card

Years

2023 - 2023

Years statistic card

Associated BioSamples

None/not available

Associated BioSamples statistic card

Geographic coverage

West Midlands

Geographic coverage statistic card

Lead time

2-6 months

Lead time statistic card

Summary

To use cardio-pulmonary exercise test parameters as additional prognostic tools for initial management of chronic heart failure for ACHD Patients: Fontan patients’ cohort. To correlate Gas exchange Pulmonary capacitance (GXcap) with VE/VCO2 slope, and heart failure assessment confirmation (NICE guidelines), to see if GXcap might be a possible tool for looking at mortality risk with ACHD (fontan patients), as well as chronic heart failure initial assessment (NICE guidelines).

Documentation

Cardio-Pulmonary Exercise Test (CPET) parameters in Adult Congenital Heart Disease (ACHD) (Fontan group): A Retrospective study.

Although the Fontan procedure can increase the survival rate, due to the abnormal nature of the heart there is a range of potentially life threatening complications associated with the condition. Fontan patients can experience a decreased quality of life and be subject to a higher risk of mortality.

This study aims to find out if any Cardio-Pulmonary Exercise parameters might be helpful to be used with Fontan patients that showed an increased risk of mortality due to having a minute ventilation and carbon dioxide production ratio slope of >32.9.

Another aim of this study is to determine if gas exchange capacitance is a good indicator for pulmonary arterial hypertension, a cardiac condition which could lead to chronic heart failure if untreated. Although the Fontan procedure can increase the survival rate, due to the abnormal nature of the heart there is a range of potentially life threatening complications associated with the condition. Fontan patients can experience a decreased quality of life and be subject to a higher risk of mortality.

Dataset type

Health and disease

Keywords

Dataset and BioSample Aliases

Provenance

Purpose of dataset collection

Study

Source of data extraction

Machine generated

Collection source setting

Secondary care - In-patients

Patient pathway description

Test results during admission period.

Image contrast

Not stated

Biological sample availability

None/not available

Details

Publishing frequency

Static

Version

1.0.0

Modified

13/05/2026

Distribution release date

17/06/2023

Citation Requirements

This publication uses data from the PATHWAY, an ethically approved Research Data Hub (NRES Reference 22/EE/0161)

Coverage

Start date

01/01/2023

End date

01/06/2023

Time lag

2-6 months

Geographic coverage

West Midlands

Follow-up

0 - 6 Months

Accessibility

Language

en

Alignment with standardised data models

LOCAL

Controlled vocabulary

ICD10, NHS NATIONAL CODES

Format

SQL

Data Access Request

Dataset pipeline status

Not available

Access rights

Information Governance and Ethics - West Midlands Secure Data Environment (https://westmidlandssde.nhs.uk/information-governance-and-ethics)

Time to dataset access

2-6 months

Access request cost

Please email wmsde@uhb.nhs.uk

Access method category

TRE/SDE

Access service description

Data Request Process - West Midlands Secure Data Environment (https://westmidlandssde.nhs.uk/research/data-request)

Data use limitation

General research use

Data use requirements

Ethics approval required,Project-specific restrictions

Data Controller

University Hospitals Birmingham NHS Foundation Trust

Data Processor

University Hospitals Birmingham NHS Foundation Trust

Dataset Types: Health and disease


Collection Sources: Secondary care - In-patients