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Longitudinal hospital prescribing data for >48,000 deeply phenotyped patients

Population Size

79,287

People

Years

2017 - 2020

Associated BioSamples

None/not available

Geographic coverage

United Kingdom

England

Lead time

1-2 months

Summary

Deeply phenotyped dataset of longitudinal prescribing data for >48,000 patients from 2017 onwards. Investigation, intervention and treatment data. Granular co-morbidities, serial physiology readings, blood biomarkers with outcome data.

Documentation

Background. The Healthcare Safety Investigation Branch (HSIB) published a report in 2020 reviewing the need to have a better method of identifying and preventing medication errors. 237 million medications errors occur in England per year. 5% of hospital admissions are related to medication errors, side effects or drug/drug interactions. Older patients, those with multiple long-term conditions and polypharmacy are most likely to experience the worse outcomes from medicine related harm. This dataset provides highly detailed medicine prescribing, indication, administration and patient outcome data, focusing on hospitalised patients in acute care.

PIONEER geography. The West Midlands (WM) has a population of 5.9 million and includes a diverse ethnic and socio-economic mix.

EHR. UHB is one of the largest NHS Trusts in England, providing direct acute services and specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds and an expanded 250 ITU bed capacity during COVID. UHB runs a fully electronic healthcare record (EHR) (PICS; Birmingham Systems), a shared primary and secondary care record (Your Care Connected) and a patient portal “My Health”.

Scope: All hospitalised patients in UHB Acute Medicine (AMU) and Emergency Departments (ED) from November 2017 to October 2020, curated to focus on medicines reconciliation. Longitudinal and individually linked, so that the preceding and subsequent health journey can be mapped and healthcare utilisation prior to and after admission understood. The dataset includes highly granular patient demographics and co-morbidities taken from ICD-10. Serial, structured data pertaining to acute care process (timings and wards). Along with presenting complaints, physiology readings (NEWS 2 and SEWS score). Includes all prescribed treatments, drug history, medication history and pharmacy interventions.

Available supplementary data: Matched controls; ambulance, OMOP data, synthetic data.

Available supplementary support: Analytics, Model build, validation and refinement; A.I.; Data partner support for ETL (extract, transform & load) process, Clinical expertise, Patient & end-user access, Purchaser access, Regulatory requirements, Data-driven trials, “fast screen” services.

Dataset type
Health and disease, Treatments/Interventions
Dataset sub-type
Not applicable
Dataset population size
79287

Keywords

Hospitalised patients, Acute Medicine, Emergency Departments, Medicines reconciliation, prescribing, administration, antibiotics, antivirals, angina, Myocardial Infarction, digoxin, Intravenous fluids, missed doses, medicines, tablets, infusions, nebulisers, subcutaneous, intramuscular, Longitudinal, individually linked, health journey, healthcare utilisation, Patient, demographics, co-morbidities, ICD-10, Serial, Structured, acute care process, time stamped, wards, presenting complaints, physiology readings, NEWS2, SEWS, drug history, medication history, pharmacy interventions, staff grades

Observations

Observed Node
Disambiguating Description
Measured Value
Measured Property
Observation Date

Persons

79,287 admissions from AMU and ED between 01-11-2017 and 01-10-2020

79287

Count

15 Feb 2022

Provenance

Purpose of dataset collection
Care
Source of data extraction
EPR
Collection source setting
Secondary care - Accident and Emergency, Secondary care - In-patients
Patient pathway description
Data is representative of the multi-ethnicity population within the West Midlands (42% non white). Data includes all patients admitted during this timeframe, with National data Opt Outs applied, and therefore is representative of admissions to secondary care. Data focuses on in-patient stay in hospital during the acute episode but can be supplemented on request to include previous and subsequent hospital contacts (including outpatient appointments) and ambulance, 111, 999 data.
Image contrast
Not stated
Biological sample availability
None/not available

Structural Metadata

Details

Publishing frequency
Quarterly
Version
1.0.0
Modified

08/10/2024

Distribution release date

15/02/2022

Citation Requirements
This publication uses data from PIONEER, an ethically approved database and analytical environment (East Midlands Derby Research Ethics 20/EM/0158)

Coverage

Start date

01/11/2017

End date

30/09/2020

Time lag
Other
Geographic coverage
United Kingdom, England, West Midlands
Minimum age range
18
Maximum age range
110
Follow-up
1 - 10 Years

Accessibility

Language
en
Alignment with standardised data models
LOCAL
Controlled vocabulary
ICD10
Format
SQL

Data Access Request

Dataset pipeline status
Available
Time to dataset access
1-2 months
Access request cost
www.pioneerdatahub.co.uk/data/data-services-costs/
Access method category
TRE/SDE
Access service description

Trusted Research Environments (TRE) are built using Microsoft Azure services and hosted in the UK to provide research teams a safe, secure and agile environment which allows users to quickly analyse, interpret and form an enriched view of primary care information through a range of integrated datasets.

Health data collated from multiple sources is ingested into a secure data lake which will then allow subsets of data to be made available to research teams on approval of a data request. Once approved a customer specific TRE is made available with a standard set of leading analytical tools from Microsoft including Azure Databricks, Azure Machine Learning, Azure SQL and Azure Synapse (for large-scale data warehouses). Specific tools can be provided at an additional cost over the standard platform data access charge and the PIONEER team will work with you to determine your exact needs.

Access to the TRE is managed using the latest virtual desktop technology to provide a safe and secure end-user experience. By utilising leading edge design PIONEER are able to create TREs rapidly to enable us to service any customer requirement.

Jurisdiction
GB-ENG
Data use limitation
Research use only
Data use requirements
Project-specific restrictions
Data Controller
University Hospitals Birmingham NHS Foundation Trust

Dataset Types: Health and disease, Treatments/Interventions


Collection Sources: Secondary care - Accident and Emergency, Secondary care - In-patients