Bookmarks
Prospective Observation of Fibrosis in the Lung Clinical Endpoints
Population Size
Not reported
Years
2010 - 2017
Associated BioSamples
Other
Geographic coverage
United Kingdom
England
Lead time
Not applicable
Summary
The PROFILE study is a longitudinal observational study of patients with Idiopathic Pulmonary Fibrosis and Nonspecific Interstitial Pneumonitis. Patients were recruited to the study within 6 months of diagnosis and followed up for three years.
Documentation
https://clinicaltrials.gov/ct2/show/NCT01134822
The PROFILE study is a longitudinal observational study of patients with Idiopathic Pulmonary Fibrosis and Non Specific Interstitial Pneumonitis. Patients were recruited to the study within 6 months of diagnosis and followed up for three years with physiological, biological, genetic and quality of life assessments assessments at various intervals over these three years. The aim of this study was to understand the natural history of fibrotic lung disease and identify factors that would be able to predict the heterogenous disease course amongst these patients.
Dataset type
Health and disease
Dataset sub-type
Not applicable
Keywords
Clinical, Lung, Idiopathic Pulmonary Fibrosis, Observation, BREATHE
Provenance
Collection source setting
Clinic, Primary care - Clinic
Image contrast
Not stated
Biological sample availability
Other
Details
Publishing frequency
Static
Version
5.0.0
Modified
08/10/2024
Distribution release date
05/10/2017
Citation Requirements
The PROFILE (Central England) cohort was generated at The Nottingham University NIHR respiratory Biomedical Research Unit with funding from a Medical Research Council (MRC MICA award G0901226).
Coverage
Start date
26/07/2010
End date
05/10/2017
Time lag
Not applicable
Geographic coverage
United Kingdom, England
Minimum age range
30
Maximum age range
89
Follow-up
1 - 10 Years
Accessibility
Language
en
Controlled vocabulary
LOCAL, READ, NHS NATIONAL CODES
Format
CSV
Data Access Request
Dataset pipeline status
Not available
Access rights
Time to dataset access
Not applicable
Access request cost
Data provision is free from SAIL. Overall project costing depends on the number of people that require access to the SAIL Gateway, the activities that SAIL needs to complete (e.g. loading non-standard datasets), data refreshes, analytical work required, disclosure control process, and special case technological requirements
Jurisdiction
GB
Data use limitation
General research use
Data use requirements
Project-specific restrictions
Data Controller
BREATHE
Data Processor
BREATHE