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Prospective Observation of Fibrosis in the Lung Clinical Endpoints

Population Size

Not reported
Population Size statistic card

Years

2010 - 2017

Years statistic card

Associated BioSamples

Other

Associated BioSamples statistic card

Geographic coverage

United Kingdom

England

Geographic coverage statistic card

Lead time

Not applicable

Lead time statistic card

Summary

The PROFILE study is a longitudinal observational study of patients with Idiopathic Pulmonary Fibrosis and Nonspecific Interstitial Pneumonitis. Patients were recruited to the study within 6 months of diagnosis and followed up for three years.

Documentation

https://clinicaltrials.gov/ct2/show/NCT01134822

The PROFILE study is a longitudinal observational study of patients with Idiopathic Pulmonary Fibrosis and Non Specific Interstitial Pneumonitis. Patients were recruited to the study within 6 months of diagnosis and followed up for three years with physiological, biological, genetic and quality of life assessments assessments at various intervals over these three years. The aim of this study was to understand the natural history of fibrotic lung disease and identify factors that would be able to predict the heterogenous disease course amongst these patients.

Dataset type

Health and disease

Dataset sub-type

Not applicable

Keywords

Provenance

Collection source setting

Clinic, Primary care - Clinic

Image contrast

Not stated

Biological sample availability

Other

Details

Publishing frequency

Static

Version

5.0.0

Modified

08/10/2024

Distribution release date

05/10/2017

Citation Requirements

The PROFILE (Central England) cohort was generated at The Nottingham University NIHR respiratory Biomedical Research Unit with funding from a Medical Research Council (MRC MICA award G0901226).

Coverage

Start date

26/07/2010

End date

05/10/2017

Time lag

Not applicable

Geographic coverage

United Kingdom, England

Minimum age range

30

Maximum age range

89

Follow-up

1 - 10 Years

Accessibility

Language

en

Controlled vocabulary

LOCAL, READ, NHS NATIONAL CODES

Format

CSV

Data Access Request

Dataset pipeline status

Not available

Time to dataset access

Not applicable

Access request cost

Data provision is free from SAIL. Overall project costing depends on the number of people that require access to the SAIL Gateway, the activities that SAIL needs to complete (e.g. loading non-standard datasets), data refreshes, analytical work required, disclosure control process, and special case technological requirements

Jurisdiction

GB

Data use limitation

General research use

Data use requirements

Project-specific restrictions

Data Controller

BREATHE

Data Processor

BREATHE

Dataset Types: Health and disease


Collection Sources: Clinic, Primary care - Clinic

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