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Prospective Observation of Fibrosis in the Lung Clinical Endpoints

Population Size

Not reported

Years

2010 - 2017

Associated BioSamples

Other

Geographic coverage

United Kingdom

England

Lead time

Not applicable

Summary

The PROFILE study is a longitudinal observational study of patients with Idiopathic Pulmonary Fibrosis and Nonspecific Interstitial Pneumonitis. Patients were recruited to the study within 6 months of diagnosis and followed up for three years.

Documentation

https://clinicaltrials.gov/ct2/show/NCT01134822

The PROFILE study is a longitudinal observational study of patients with Idiopathic Pulmonary Fibrosis and Non Specific Interstitial Pneumonitis. Patients were recruited to the study within 6 months of diagnosis and followed up for three years with physiological, biological, genetic and quality of life assessments assessments at various intervals over these three years. The aim of this study was to understand the natural history of fibrotic lung disease and identify factors that would be able to predict the heterogenous disease course amongst these patients.

Dataset type
Health and disease
Dataset sub-type
Not applicable

Keywords

Clinical, Lung, Idiopathic Pulmonary Fibrosis, Observation, BREATHE

Provenance

Collection source setting
Clinic, Primary care - Clinic
Image contrast
Not stated
Biological sample availability
Other

Details

Publishing frequency
Static
Version
5.0.0
Modified

08/10/2024

Distribution release date

05/10/2017

Citation Requirements
The PROFILE (Central England) cohort was generated at The Nottingham University NIHR respiratory Biomedical Research Unit with funding from a Medical Research Council (MRC MICA award G0901226).

Coverage

Start date

26/07/2010

End date

05/10/2017

Time lag
Not applicable
Geographic coverage
United Kingdom, England
Minimum age range
30
Maximum age range
89
Follow-up
1 - 10 Years

Accessibility

Language
en
Controlled vocabulary
LOCAL, READ, NHS NATIONAL CODES
Format
CSV

Data Access Request

Dataset pipeline status
Not available
Access rights
https://saildatabank.com/application-process/
Time to dataset access
Not applicable
Access request cost
Data provision is free from SAIL. Overall project costing depends on the number of people that require access to the SAIL Gateway, the activities that SAIL needs to complete (e.g. loading non-standard datasets), data refreshes, analytical work required, disclosure control process, and special case technological requirements
Jurisdiction
GB
Data use limitation
General research use
Data use requirements
Project-specific restrictions
Data Controller
BREATHE
Data Processor
BREATHE

Dataset Types: Health and disease

Collection Sources: Clinic, Primary care - Clinic