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Extended Cohort for E-health, Environment and DNA (EXCEED)

Population Size

Not reported
Population Size statistic card

Years

1950 - 2018

Years statistic card

Associated BioSamples

Saliva

Whole blood

Associated BioSamples statistic card

Geographic coverage

United Kingdom

England

...see more

Geographic coverage statistic card

Lead time

2-4 weeks

Lead time statistic card

Summary

EXCEED is a longitudinal population-based cohort which facilitates investigation of genetic, environmental and lifestyle-related determinants of a broad range of diseases and of multiple morbidity.

Documentation

https://exceed.org.uk/

EXCEED has been described in a cohort profile paper accessible here: https://academic.oup.com/ije/article/48/3/678/5485771

EXCEED is a longitudinal population-based cohort which facilitates investigation of genetic, environmental and lifestyle-related determinants of a broad range of diseases and of multiple morbidity through data collected at baseline and via electronic healthcare record linkage. Recruitment has taken place in Leicester, Leicestershire and Rutland since 2013 and is ongoing, with >10,650 participants aged 30-69 to date. The population of Leicester is diverse and additional recruitment from the local South Asian community is ongoing. Participants provided a DNA sample, have consented to follow-up for up to 25 years through electronic health records and additional bespoke data collection is planned. Data available includes baseline demographics, anthropometry, spirometry, lifestyle factors (smoking and alcohol use) and longitudinal health information from primary care records, with additional linkage to other EHR datasets planned. Patients have consented to be contacted for recall-by-genotype and recall-by-phenotype sub-studies. Genome-wide genotype data are available via EGA for 5218 individuals.

Dataset type

Health and disease

Dataset sub-type

Not applicable

Keywords

Provenance

Purpose of dataset collection

Study

Collection source setting

Clinic, Primary care - Clinic, Secondary care - Accident and Emergency, Secondary care - Outpatients, Secondary care - In-patients, Community, Home

Patient pathway description

The population includes only covers adults (over 18) who live within certain areas: Midlands, UK. Data is survey data, clinic assessments, and linkable to primary and secondary care.

Image contrast

Not stated

Biological sample availability

Saliva,Whole blood

Structural Metadata

Details

Publishing frequency

Annual

Version

5.0.0

Modified

08/10/2024

Distribution release date

16/12/2019

Citation Requirements

EXCEED

Coverage

Start date

01/01/1950

End date

03/08/2018

Time lag

Not applicable

Geographic coverage

United Kingdom, England, East Midlands, West Midlands

Minimum age range

18

Maximum age range

70

Follow-up

10 Years

Accessibility

Language

en

Controlled vocabulary

READ

Format

CSV

Data Access Request

Dataset pipeline status

Not available

Time to dataset access

2-4 weeks

Access request cost

Data provision is free from SAIL. Overall project costing depends on the number of people that require access to the SAIL Gateway, the activities that SAIL needs to complete (e.g. loading non-standard datasets), data refreshes, analytical work required, disclosure control process, and special case technological requirements

Access method category

TRE/SDE

Access service description

Jurisdiction

GB

Data use limitation

Research-specific restrictions

Data use requirements

Project-specific restrictions

Data Controller

BREATHE

Data Processor

BREATHE

Dataset Types: Health and disease


Collection Sources: Clinic, Primary care - Clinic, Secondary care - Accident and Emergency, Secondary care - Outpatients, Secondary care - In-patients, Community, Home

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