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Extended Cohort for E-health, Environment and DNA (EXCEED)
Population Size
Years
1950 - 2018
Associated BioSamples
Saliva
Whole blood
Geographic coverage
United Kingdom
England
...see more
Lead time
Not applicable
Summary
Documentation
EXCEED has been described in a cohort profile paper accessible here: https://academic.oup.com/ije/article/48/3/678/5485771
EXCEED is a longitudinal population-based cohort which facilitates investigation of genetic, environmental and lifestyle-related determinants of a broad range of diseases and of multiple morbidity through data collected at baseline and via electronic healthcare record linkage. Recruitment has taken place in Leicester, Leicestershire and Rutland since 2013 and is ongoing, with >10,650 participants aged 30-69 to date. The population of Leicester is diverse and additional recruitment from the local South Asian community is ongoing. Participants provided a DNA sample, have consented to follow-up for up to 25 years through electronic health records and additional bespoke data collection is planned. Data available includes baseline demographics, anthropometry, spirometry, lifestyle factors (smoking and alcohol use) and longitudinal health information from primary care records, with additional linkage to other EHR datasets planned. Patients have consented to be contacted for recall-by-genotype and recall-by-phenotype sub-studies. Genome-wide genotype data are available via EGA for 5218 individuals.
Keywords
Provenance
Structural Metadata
Details
08/10/2024
16/12/2019
Coverage
01/01/1950
03/08/2018
10 Years