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Extended Cohort for E-health, Environment and DNA (EXCEED)

Population Size

Not reported

Years

1950 - 2018

Associated BioSamples

Saliva

Whole blood

Geographic coverage

United Kingdom

England

...see more

Lead time

Not applicable

Summary

EXCEED is a longitudinal population-based cohort which facilitates investigation of genetic, environmental and lifestyle-related determinants of a broad range of diseases and of multiple morbidity.

Documentation

https://exceed.org.uk/

EXCEED has been described in a cohort profile paper accessible here: https://academic.oup.com/ije/article/48/3/678/5485771

EXCEED is a longitudinal population-based cohort which facilitates investigation of genetic, environmental and lifestyle-related determinants of a broad range of diseases and of multiple morbidity through data collected at baseline and via electronic healthcare record linkage. Recruitment has taken place in Leicester, Leicestershire and Rutland since 2013 and is ongoing, with >10,650 participants aged 30-69 to date. The population of Leicester is diverse and additional recruitment from the local South Asian community is ongoing. Participants provided a DNA sample, have consented to follow-up for up to 25 years through electronic health records and additional bespoke data collection is planned. Data available includes baseline demographics, anthropometry, spirometry, lifestyle factors (smoking and alcohol use) and longitudinal health information from primary care records, with additional linkage to other EHR datasets planned. Patients have consented to be contacted for recall-by-genotype and recall-by-phenotype sub-studies. Genome-wide genotype data are available via EGA for 5218 individuals.

Dataset type
Health and disease
Dataset sub-type
Not applicable

Keywords

Genetic, Electronic, Lifestyle, Environment, Cohort, Population, EXCEED, BREATHE

Provenance

Purpose of dataset collection
Study
Collection source setting
Clinic, Primary care - Clinic, Secondary care - Accident and Emergency, Secondary care - Outpatients, Secondary care - In-patients, Community, Home
Patient pathway description
The population includes only covers adults (over 18) who live within certain areas: Midlands, UK. Data is survey data, clinic assessments, and linkable to primary and secondary care.
Image contrast
Not stated
Biological sample availability
Saliva,Whole blood

Structural Metadata

Details

Publishing frequency
Annual
Version
5.0.0
Modified

08/10/2024

Distribution release date

16/12/2019

Citation Requirements
EXCEED

Coverage

Start date

01/01/1950

End date

03/08/2018

Time lag
Not applicable
Geographic coverage
United Kingdom, England, East Midlands, West Midlands
Minimum age range
18
Maximum age range
70
Follow-up

10 Years

Accessibility

Language
en
Controlled vocabulary
READ
Format
CSV

Data Access Request

Dataset pipeline status
Not available
Time to dataset access
Not applicable
Access request cost
Data provision is free from SAIL. Overall project costing depends on the number of people that require access to the SAIL Gateway, the activities that SAIL needs to complete (e.g. loading non-standard datasets), data refreshes, analytical work required, disclosure control process, and special case technological requirements
Access method category
TRE/SDE
Access service description
Jurisdiction
GB
Data use limitation
Research-specific restrictions
Data use requirements
Project-specific restrictions
Data Controller
BREATHE
Data Processor
BREATHE

Dataset Types: Health and disease


Collection Sources: Clinic, Primary care - Clinic, Secondary care - Accident and Emergency, Secondary care - Outpatients, Secondary care - In-patients, Community, Home