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Generation Scotland: Scottish Family Health Study

Population Size

24,000

People

Years

2006 - 2011

Associated BioSamples

DNA

Plasma

...see more

Geographic coverage

United Kingdom

Scotland

Lead time

Not applicable

Summary

A biobank of data and samples for medical research. GS:SFHS is an intensively phenotyped, family-based cohort for the study of the genetic basis of common complex diseases and response to treatments, with consent to record linkage and recontact.

Documentation

A collaboration between the Universities of Edinburgh, Glasgow, Dundee and Aberdeen, and NHS Scotland, to provide resources for genetic and medical research.

The Scottish Family Health Study (GS:SFHS) is a collection of genetic, medical, familThe Generation Scotland: Scottish Family Health Study (GS:SFHS) is a collection of genetic, medical, family history and lifestyle information from over 24, 000 volunteers. It is an intensively phenotyped, family-based cohort for the study of the genetic basis of common complex diseases and response to treatments. The cohort includes just over 24, 000 participants recruited 2006-11, with most consenting to record linkage and recontact. Participants gave blood or saliva samples (for processing, biochemistry and cryopreservation) and a urine sample. The blood or saliva samples were processed to DNA and extensive genotyping was carried out on over 20, 000 participants by 2015, with DNA methylation assayed on 10, 000 by 2019. Follow up is primarily through record linkage and includes linkage to GP records and also via online questionnaires, including CovidLife.y history and lifestyle information from over 24, 000 volunteers. it is an intensively phenotyped, family-based cohort for the study of the genetic basis of common complex diseases and response to treatments. The cohort includes just over 24, 000 participants recruited 2006-11, with most consenting to record linkage and recontact. Participants gave blood or saliva samples (for processing, biochemistry and cryopreservation) and a urine sample. The blood or saliva samples were processed to DNA and extensive genotyping was carried out on over 20, 000 participants by 2015, with DNA methylation assayed on 10, 000 by 2019.

Dataset type
Health and disease
Dataset sub-type
Not applicable
Dataset population size
24,000

Keywords

Edinburgh, Generation, NHS Scotland, Scotland, UKCRC Tissue Directory, genetic, Fit and well, Glasgow, Alleviate, Pain, Pain Hub, Dundee, Aberdeen

Observations

Observed Node
Disambiguating Description
Measured Value
Measured Property
Observation Date

Persons

Adults born before 1992, residing in Scotland at time of recruitment

24000

Count

10 May 2011

Provenance

Image contrast
Not stated
Biological sample availability
DNA, Plasma, Serum, Urine, Whole blood

Details

Publishing frequency
Static
Version
5.0.0
Modified

08/10/2024

Citation Requirements
University of Edinburgh

Coverage

Start date

23/01/2006

End date

10/05/2011

Time lag
Not applicable
Geographic coverage
United Kingdom, Scotland
Minimum age range
18
Maximum age range
90

Accessibility

Language
en
Controlled vocabulary
OPCS4, READ, ICD10, ICD9, NHS SCOTLAND NATIONAL CODES, LOCAL
Format
text/csv

Data Access Request

Dataset pipeline status
Not available
Time to dataset access
Not applicable
Jurisdiction
GB-SCT
Data use limitation
General research use, Commercial research use, Geographical restrictions
Data use requirements
Return to database or resource, Collaboration required
Data Controller
University of Edinburgh

Dataset Types: Health and disease


Collection Sources: No collection sources listed