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POUT-T

Population Size

Not reported
Population Size statistic card

Years

2014

Years statistic card

Associated BioSamples

Plasma

Urine

Associated BioSamples statistic card

Geographic coverage

United Kingdom

England

Geographic coverage statistic card

Lead time

Other

Lead time statistic card

Summary

Collection of samples and data across the following diseases: Malignant tumour of urinary bladder (disorder), Transitional cell carcinoma.

Documentation

POUT-T: The translational substudy of a phase III randomised trial of peri-operative chemotherapy versus surveillance in upper tract urothelial cancer. The objectives of POUT-T are: to investigate the molecular pathogenesis of Upper Tract Urothelial Carcinoma (UTUC); to identify prognostic and predictive biomarkers of UTUC; and to identify diagnostic biomarkers of UTUC. POUT-T participants are requested to provide the following specimens pre-operatively, post operatively, 6 months following surgery, and at disease recurrence: whole blood for germline DNA analysis; whole blood for cell-free DNA analysis; first morning urine for DNA, proteome and metabolome analyses. In addition, paraffin-embedded tumour tissue from nephro-ureterectomy is requested for immunohistochemistry and DNA/RNA analyses.

Dataset type

Health and disease

Dataset sub-type

Not applicable

Keywords

Provenance

Image contrast

Not stated

Biological sample availability

Plasma,Urine,Whole blood

Details

Publishing frequency

Other

Version

1.0.0

Modified

08/10/2024

Citation Requirements

In Progress

Coverage

Start date

01/01/2014

Time lag

Variable

Geographic coverage

United Kingdom, England

Minimum age range

15

Maximum age range

150

Accessibility

Language

en

Controlled vocabulary

LOCAL

Format

In Progress

Data Access Request

Dataset pipeline status

Not available

Access rights

Please contact the publisher using Contact Point details provided.

Time to dataset access

Other

Access request cost

Not specified

Access method category

Varies based on project

Data Controller

The Institute of Cancer Research

Dataset Types: Health and disease


Collection Sources:

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