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NICAM: Nilotinib treatment for c-KIT mutated advanced AMM

Population Size

Not reported

Years

2009

Associated BioSamples

Availability to be confirmed

Geographic coverage

United Kingdom

England

Lead time

Other

Summary

Collection of samples and data across the following diseases: Malignant melanoma of eye (disorder).

Documentation

Phase II single arm study evaluating the activity of nilotinib in rare c-KIT mutated acral and mucosal melanoma (AMM). Entry into the trial is a 2 step process. Patients presenting with AMM are first registered (Step 1) for screening including confirmation of c-KIT mutation status. Eligible patients who proceed to study entry (step 2) commence treatment with nilotinib 400 mgs twice daily for as long as they continue to benefit from treatment.
Dataset type
Health and disease
Dataset sub-type
Not applicable

Keywords

Malignant melanoma of eye (disorder), UKCRC Tissue Directory, NICAM, c-KIT, Nilotinib, AMM

Provenance

Image contrast
Not stated
Biological sample availability
Availability to be confirmed

Details

Publishing frequency
Other
Version
1.0.0
Modified

08/10/2024

Citation Requirements
In Progress

Coverage

Start date

01/01/2009

Time lag
Variable
Geographic coverage
United Kingdom, England

Accessibility

Language
en
Controlled vocabulary
LOCAL
Format
In Progress

Data Access Request

Dataset pipeline status
Not available
Access rights
Please contact the publisher using Contact Point details provided.
Time to dataset access
Other
Access request cost
Not specified
Access method category
Varies based on project
Data Controller
The Institute of Cancer Research

Dataset Types: Health and disease


Collection Sources: