NIHR Exeter Clinical Research Facility is a partnership between the University of Exeter Medical School and the Royal Devon and Exeter Foundation Trust. It is dedicated to facilitation of clinical and translational research. We have two main collections: the Peninsula Research Bank (PRB) and the Royal Devon and Exeter Tissue Bank (RDETB). The PRB has ethics to accept gifted samples from completed studies, and the bulk of the collection is from a dedicated biobank collection called EXTEND (the EXeter TEN thousanD), which aims to recruit one in ten of the local Exeter population. The majority (c. 75%) of our studies are local CI led, and we specialise mainly in diabetes, obesity and related pathologies. However, the majority of people within the EXTEND study are fit and well. The RDETB has overarching ethics to collect samples from diagnostic procedures with patients' consent. Each collection within the RDETB uses a standardised consent and collection approach to obtain material that would otherwise be destroyed or not retained. There is scope for prospective studies recruiting through the RDETB. Both collections have a steering committee controlling access, including lay members from within the biobank. There is a standardised approach for requests and the committee sits once a month. In addition, access to gifted samples within the PRB will involve contact with the PI, where possible. Some studies have additional steering committees where they have been carried out in consortia with other centres. First contact via this directory is encouraged, to establish your needs and our ability to meet them.