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UK MND Collections

Population Size

Not reported
Population Size statistic card

Years

2003

Years statistic card

Associated BioSamples

DNA

Immortalized cell lines

Associated BioSamples statistic card

Geographic coverage

United Kingdom

England

Geographic coverage statistic card

Lead time

Other

Lead time statistic card

Summary

Collection of samples and data across the following diseases: Motor neuron disease (disorder)

Documentation

The UK MND Collections (formerly known as the UK MND DNA Bank) was established to provide the international research community with a resource that would help to identify and understand the causative and disease modifying factors involved with motor neurone disease. These samples are available for research into MND and associated conditions such as fronto-temporal dementia only. The UK MND Collections combines more than 3,000 biological samples and accompanying clinical information; as well as epidemiology data from 400 participants, including people with MND, controls and family members. The DNA Bank was the original Collection of whole genome DNA from over 3,000 blood samples, which are stored at CIGMR (Centre for Integrated Genomic Medical Research) in Manchester, UK. The DNA Bank also has clinical information (divided into a minimum and extended dataset) which is available to researchers. The Cell Lines Collection offers a sub set of the DNA Bank samples as EBV-transformed lymphoblastoid cell lines and peripheral blood lymphocytes. This was originally set up as an everlasting supply of DNA, with the lymphoblastoid cell lines now available to researchers to help them understand how the disease is developing. The Epidemiology Collection has just over 200 patient and matched control blood samples with extensive environmental and lifestyle data (both from self-report questionnaires and telephone interviews) available to researchers. More information on the DNA and cell bank is available in Smith et al BMC Genetics (2015) 16:84.

Dataset type

Health and disease

Dataset sub-type

Not applicable

Keywords

Provenance

Image contrast

Not stated

Biological sample availability

DNA,Immortalized cell lines

Details

Publishing frequency

Other

Version

1.0.0

Modified

08/10/2024

Distribution release date

01/11/2019

Citation Requirements

In Progress

Coverage

Start date

01/01/2003

Time lag

Variable

Geographic coverage

United Kingdom, England

Minimum age range

15

Maximum age range

150

Accessibility

Language

en

Controlled vocabulary

LOCAL

Format

In Progress

Data Access Request

Dataset pipeline status

Not available

Access rights

Please contact the publisher using Contact Point details provided

Time to dataset access

Other

Access request cost

Not specified

Access method category

Varies based on project

Data Controller

MND Association

Dataset Types: Health and disease


Collection Sources:

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