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The Cleft Collective

Population Size

Not reported
Population Size statistic card

Years

2013

Years statistic card

Associated BioSamples

Availability to be confirmed

Associated BioSamples statistic card

Geographic coverage

United Kingdom

England

Geographic coverage statistic card

Lead time

Other

Lead time statistic card

Summary

Collection of samples and data across the following diseases: Orofacial cleft (disorder)

Documentation

The Cleft Collective is a longitudinal cohort study looking to investigate the biological and environmental causes of cleft and the best treatments of cleft on those affected and their families. The study comprises two separate cohorts, a Birth Cohort and a 5-year-old Cohort. The birth cohort is further split into two sub-groups, postnatal and antenatal, allocation to these groups is determined by the time of recruitment. Recruitment to the two cohorts is currently ongoing across the UK. A large amount of phenotypic and environmental exposure data is being collected via questionnaires and record linkage. A data dictionary, available on the study website, contains details of all the available data.
As a minimum, biological mother and affected child are recruited to the study. Where possible, biological father or mother's partner is also recruited. In addition, the study aims to recruit unaffected and affected siblings for a small proportion of the cohort.
Biological samples are collected from all participants. Parents and siblings of both cohorts and affected children of the 5-year-old cohort provide saliva samples. Residual tissue and blood samples are collected from affected children recruited to the birth cohort. In addition, cord blood samples are collected from families recruited to the antenatal strand.

Dataset type

Health and disease

Dataset sub-type

Not applicable

Keywords

Provenance

Image contrast

Not stated

Biological sample availability

Availability to be confirmed

Details

Publishing frequency

Other

Version

1.0.0

Modified

08/10/2024

Distribution release date

08/08/2019

Citation Requirements

In Progress

Coverage

Start date

01/01/2013

Time lag

Variable

Geographic coverage

United Kingdom, England

Maximum age range

150

Accessibility

Language

en

Controlled vocabulary

LOCAL

Format

In Progress

Data Access Request

Dataset pipeline status

Not available

Access rights

Please contact the publisher using Contact Point details provided

Time to dataset access

Other

Access request cost

Not specified

Access method category

Varies based on project

Data Controller

The University of Bristol

Dataset Types: Health and disease


Collection Sources:

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