Bookmarks
Wellcome Sanger Institute: Whole Exome Sequencing
Population Size
Not reported
Years
2016
Associated BioSamples
DNA
Plasma
Geographic coverage
United Kingdom
Lead time
2-6 months
Summary
There is a substantial overlap between the NIHR IBD BioResource and the IBD UK Genetics Consortium (IBDGC). The NIHR BioResource provides some DNA samples. IBDGC data is being provided by the Wellcome Sanger Institute, who are performing the sequencing.
Documentation
There is a substantial overlap between the participants in the NIHR IBD BioResource and the long-running IBD UK Genetics Consortium (IBDGC). The Wellcome Sanger Institute performs the sequencing work for the IBDGC. The NIHR BioResource provides DNA samples to this initiative. For those samples, and where there is an additional overlap, e.g. because a participant has been seen before and therefore no new sample is required, this data is being provided to the Gut Reaction Hub by the Wellcome Sanger Institute.
Dataset type
Health and disease, Omics
Dataset sub-type
Oral and gastrointestinal
Keywords
IBD, Crohn's, colitis, WES, Exome, Genome, Sequencing
Observations
Observed Node | Disambiguating Description | Measured Value | Measured Property | Observation Date |
|---|---|---|---|---|
Events | Whole Exome Sequences - CRAM files | 6996 | COUNT | 01 Sep 2021 |
Events | Whole Exome Sequences - VCF joint file | 6996 | COUNT | 01 Sep 2021 |
Provenance
Purpose of dataset collection
Study
Source of data extraction
Machine generated
Collection source setting
Other
Image contrast
Not stated
Biological sample availability
DNA,Plasma,Serum
Details
Publishing frequency
Irregular
Version
1.0.0
Modified
08/10/2024
Citation Requirements
IBD Genetics Consortium UK, Welcome Sanger Institute
Coverage
Start date
13/01/2016
Time lag
More than 6 months
Geographic coverage
United Kingdom
Minimum age range
18
Maximum age range
85
Follow-up
1 - 10 Years
Accessibility
Language
en
Controlled vocabulary
LOCAL
Format
text, vcf
Data Access Request
Dataset pipeline status
Not available
Access rights
Time to dataset access
2-6 months
Access request cost
Access method category
TRE/SDE
Access service description
Data may only be accessed in an environment approved by the IBDGC UK.
Jurisdiction
GB-GB
Data use limitation
Research use only
Data use requirements
Institution-specific restrictions,Project-specific restrictions,Return to database or resource,Time limit on use,User-specific restriction
Data Controller
Cambridge University Hospitals NHS Foundation Trust (CUH)
Data Processor
Data processors are NIHR BioResource staff, others with Letters of Access to CUH and approved members of staff at the data centre (AIMES, https://aimes.uk/)