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Beta-blocker Stratification using MRI to assess portal pressure (B-SMaRT)

Population Size

46

People

Years

2016

Associated BioSamples

Availability to be confirmed

Geographic coverage

United Kingdom

England

Lead time

Not applicable

Summary

Provide proof of concept that quantitative haemodynamic MRI markers can stratify the efficacy of carvedilol to lower clinically significant portal hypertension in patients with cirrhosis.

Documentation

Beta-blocker Stratification using quantitative MRI techniques to assess portal pressure and Response to Treatment in patients with portal hypertension (B-SMaRT study).

To provide proof of concept that quantitative haemodynamic MRI markers can stratify the efficacy of carvedilol to lower clinically significant portal hypertension in patients with cirrhosis.

Descriptive sequential pilot study of patients with cirrhosis, portal pressure measurement, research MRI (at 3T) and endoscopy with outcomes with repeat measures in those who are given Carvedilol

Dataset type
Health and disease
Dataset sub-type
Not applicable
Dataset population size
46

Keywords

cirrhosis, portal hypertension, varices, MRI, Magnetic resonance imaging, beta-blockers, Beta blockers

Observations

Observed Node
Disambiguating Description
Measured Value
Measured Property
Observation Date

Persons

46

Count

01 Aug 2016

Provenance

Purpose of dataset collection
Study
Source of data extraction
Paper-based
Collection source setting
Secondary care - Outpatients
Patient pathway description
Secondary Care
Image contrast
Not stated
Biological sample availability
Availability to be confirmed

Details

Publishing frequency
Irregular
Version
1.0.0
Modified

08/10/2024

Citation Requirements
NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust

Coverage

Start date

01/08/2016

Time lag
Variable
Geographic coverage
United Kingdom, England, East Midlands
Minimum age range
18
Maximum age range
80
Follow-up
1 - 10 Years

Accessibility

Language
en
Controlled vocabulary
LOCAL
Format
Database

Data Access Request

Dataset pipeline status
Not available
Access rights
In Progress
Time to dataset access
Not applicable
Jurisdiction
GB-ENG
Data use limitation
General research use
Data Controller
Professor Guruprasad Aithal
Data Processor
N/A

Dataset Types: Health and disease

Collection Sources: No collection sources listed