Bookmarks
Beta-blocker Stratification using MRI to assess portal pressure (B-SMaRT)
Population Size
46
People
Years
2016
Associated BioSamples
Availability to be confirmed
Geographic coverage
United Kingdom
England
Lead time
Variable
Summary
Provide proof of concept that quantitative haemodynamic MRI markers can stratify the efficacy of carvedilol to lower clinically significant portal hypertension in patients with cirrhosis.
Documentation
Beta-blocker Stratification using quantitative MRI techniques to assess portal pressure and Response to Treatment in patients with portal hypertension (B-SMaRT study).
To provide proof of concept that quantitative haemodynamic MRI markers can stratify the efficacy of carvedilol to lower clinically significant portal hypertension in patients with cirrhosis.
Descriptive sequential pilot study of patients with cirrhosis, portal pressure measurement, research MRI (at 3T) and endoscopy with outcomes with repeat measures in those who are given Carvedilol
Dataset type
Health and disease
Dataset sub-type
Not applicable
Dataset population size
46
Keywords
cirrhosis, portal hypertension, varices, MRI, Magnetic resonance imaging, beta-blockers, Beta blockers
Observations
Observed Node | Disambiguating Description | Measured Value | Measured Property | Observation Date |
|---|---|---|---|---|
Persons | 46 | Count | 01 Aug 2016 |
Provenance
Purpose of dataset collection
Study
Source of data extraction
Paper-based
Collection source setting
Secondary care - Outpatients
Patient pathway description
Secondary Care
Image contrast
Not stated
Biological sample availability
Availability to be confirmed
Details
Publishing frequency
Irregular
Version
1.0.0
Modified
08/10/2024
Citation Requirements
NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust
Coverage
Start date
01/08/2016
Time lag
Variable
Geographic coverage
United Kingdom, England, East Midlands
Minimum age range
18
Maximum age range
80
Follow-up
1 - 10 Years
Accessibility
Language
en
Controlled vocabulary
LOCAL
Format
Database
Data Access Request
Dataset pipeline status
Not available
Access rights
In Progress
Time to dataset access
Variable
Jurisdiction
GB-ENG
Data use limitation
General research use
Data Controller
Professor Guruprasad Aithal
Data Processor
N/A