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UK BioLAM

Population Size

300

People

Years

2004

Associated BioSamples

Other

Geographic coverage

United Kingdom

England

Lead time

Not applicable

Summary

Lymphangioleiomyomatosis (LAM) is a multi-system disease of women. Metabolomics have been used to determine if metabolites downstream of mTOR and other LAM realted pathways were present or related to disease progression in a national cohort.

Documentation

Lymphangioleiomyomatosis (LAM) is a rare lung and lymphatic disease categorised by infiltration of smooth muscle type cells in the lungs and lymphatics leading to progressive respiratory impairment. The disease only effects women and is caused by a defect in one of the two proteins associated with tuberous sclerosis, tuberin and hamartin.
Dataset type
Health and disease
Dataset sub-type
Not applicable
Dataset population size
300

Keywords

Lymphangioleiomyomatosis, LAM, mTOR, mechanistic target of rapamycin, rapamycin

Observations

Observed Node
Disambiguating Description
Measured Value
Measured Property
Observation Date

Persons

300

Count

01 Oct 2004

Provenance

Purpose of dataset collection
Study
Source of data extraction
Paper-based
Collection source setting
Secondary care - In-patients
Image contrast
Not stated
Biological sample availability
Other

Structural Metadata

Details

Publishing frequency
Irregular
Version
1.0.0
Modified

08/10/2024

Coverage

Start date

01/10/2004

Time lag
Variable
Geographic coverage
United Kingdom, England
Minimum age range
18
Maximum age range
65
Follow-up
Unknown

Accessibility

Language
en
Controlled vocabulary
LOCAL
Format
csv

Data Access Request

Dataset pipeline status
Not available
Access rights
In Progress
Time to dataset access
Not applicable
Jurisdiction
GB-ENG
Data Controller
Professor Simon Johnson

Dataset Types: Health and disease


Collection Sources: No collection sources listed