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Moorfields Dry-AMD Dataset 006

Population Size

7,305

People

Years

2001

Associated BioSamples

Other

Geographic coverage

https://www.geonames.org/2648147/great-britain.html

Lead time

2-6 months

Summary

The Dry-AMD Dataset at Moorfields Eye Hospital is a longitudinal dataset consisting of routinely collected data from patients strictly with advanced dry age-related macular degeneration (AMD) and with an absence of the wet form of the disease.

Documentation

The Moorfields Dry-AMD Dataset encompasses all patients with advanced dry AMD, specifically geographic atrophy (GA), and without choroidal neovascularization, at Moorfields Eye Hospital - a leading provider of eye health services in the UK and a world-class centre of excellence for ophthalmic research and education. A detailed description of the dataset definitions can be found below.

Inclusion criteria:

  • a posterior free hand draw label of ‘Geographic’ or (ii) at least one reference in their clinical notes to ‘geographic atrophy’

Exclusion criteria:

  • Patients under the age of 50 at their most-recent imaging event
  • Patients with at least one reference in their clinical notes to ‘Stargardt’
  • Patients with a record of injections of any type
  • Patients with a posterior free hand draw label of ‘Choroidal neovascularization’

The dataset will include any imaging or clinical metadata that is available for these patients. In the instance where only one eye meets the criteria above, both eyes are included in the dataset. For these reasons, the dataset will include longitudinal data from where a patient underwent monitoring during the early and intermediate stages of the disease.

Clinical metadata includes information regarding:

  • patient demographics
  • visual acuities (predominantly measured with Early Treatment Diabetic Retinopathy Study (ETDRS) charts)
  • ocular surgeries

Additional information is provided in the ‘technical details’ tab.

The Dry-AMD dataset includes eye imaging modalities, such as:

  • Optical coherence tomography (CSO, Heidelberg, Optos, Topcon, Zeiss)
  • Colour fundus photographs (Topcon, Zeiss)
  • Ultra-wide field photographs (Optos, Zeiss)
  • Iris photographs (CSO, Zeiss)
  • Keratoscope topography (CSO)
  • Infrared photographs (Heidelberg, Topcon, Zeiss)
  • Fluorescein angiography (Heidelberg, Optos, Topcon, Zeiss)
  • Indocyanine green angiography (Heidelberg, Optos, Topcon)
  • Fundus autofluorescence (Heidelberg, Optos, Zeiss)

Imaging data from CSO is subject to additional approvals.

As of July 2024, the dataset consisted of 11,168 eyes and over 688,018 ophthalmic images.

Dataset type
Health and disease
Dataset sub-type
Not applicable
Dataset population size
7305
Associated media
https://www.insight.hdrhub.org/about-us

Keywords

Eylea, Ophthalmology, Referral, Vision, Topcon, ranibizumab, aflibercept, AMD, Wet AMD, Wet, Eye, MEH, Left, Right, Injection, Diagnosis, Eye condition, Laterality, Ophthalmology, Dry AMD, Topcon, OCT, Colour photo, Age-Related Macular Degeneration, Surgery, Modality, Heidelberg, Macular, Protocol, Cataract, Glaucoma, Diabetes, DMO, DR, Ocular, Optic, Lucentis, Eye drop, IVT, Treatment, VA, Visual Acuity, Zeiss, GA, Geographic Atrophy, Dry AMD

Observations

Observed Node
Disambiguating Description
Measured Value
Measured Property
Observation Date

Persons

11,168 Eyes with 688,018 Images

7305

Patients

30 Jun 2024

Provenance

Purpose of dataset collection
Study
Collection source setting
Clinic, Secondary care - Accident and Emergency, Secondary care - Outpatients, Secondary care - In-patients
Patient pathway description
The dataset is representative of the entire pathway for patients receiving treatment for age-related macular degeneration (AMD) at Moorfields Eye Hospital NHS Foundation Trust .
Image contrast
Not stated
Biological sample availability
Other

Structural Metadata

Details

Publishing frequency
Continuous
Version
1.0.0
Modified

08/10/2024

Coverage

Start date

01/03/2001

Time lag
1-2 weeks
Geographic coverage
https://www.geonames.org/2648147/great-britain.html
Minimum age range
38
Maximum age range
103
Follow-up

10 Years

Accessibility

Language
en
Controlled vocabulary
SNOMED CT, DM+D, NHS NATIONAL CODES
Format
CSV, Image

Data Access Request

Dataset pipeline status
Not available
Access rights
https://www.insight.hdrhub.org/researcher-area
Time to dataset access
2-6 months
Access request cost
https://www.insight.hdrhub.org/contact
Access service description
INSIGHT has established a Secure Research Environment (SRE) to provide researchers with a computing environment that meets the security levels required by regulation, with the power needed for analysis of large datasets. In addition to the SRE, INSIGHT may provide approved researchers with alternative data access methods, such as data egress, subject to meeting security conditions. For more information please visit our SRE website https://www.insight.hdrhub.org/secure-research-environment.
Jurisdiction
GB-GBN
Data use limitation
General research use
Data use requirements
Project-specific restrictions
Data Controller
Moorfields Eye Hospital NHS Foundation Trust

Dataset Types: Health and disease

Collection Sources: Clinic, Secondary care - Accident and Emergency, Secondary care - Outpatients, Secondary care - In-patients