ERA Registry

ILD42

Population-based studies indicate that the proportion of women with predialysis chronic kidney disease is higher than that of men. However, the opposite is the case for patients initiating kidney replacement therapy (KRT) for end-stage kidney disease: across all European countries as well as in the US there is a higher proportion of men on KRT. This paradox is likely due to a faster declining kidney function in men than in women, and because elderly men are less likely to choose conservative care than elderly women. A review of the sex distribution in relation to the different primary renal diseases that result in the need for KRT may contribute to the discussion on this gender-paradox. In addition, in patients with predialysis chonic kidney disease, mortality is higher in men than in women. On the other hand mortality among patients on KRT is similar in men and women. Therefore also a comparison of survival among men and women for the different primary renal diseases could provide insight into the disparities between men and women. Knowledge on sex specific primary renal disease distribution among patients on KRT might contribute to a better understanding of higher KRT incidence in men and have potential clinical implications.

10/03/2020