HDR Gateway logo
HDR Gateway logo

Bookmarks

Trends in excess mortality of adult patients on renal replacement therapy compared to the general population in Europe.

Safe People

Organisation name

ERA Registry

Safe Projects

Project ID

ILD29

Lay summary

Patients with end stage renal disease who are on renal replacement therapy (dialysis or kidney transplantation) have a high risk of death. Analyses of registry data support that survival of patients with end stage renal disease has increased over the last decade. However, it is unclear to what extent this better survival can be explained by the overall increase in survival in the general population. A US study has shown that the excess risk of all-cause mortality among end stage kidney disease patients has significantly decreased between 1995 and 2013 (3). The results of this study may however not be generalizable to Europe. Hence a new study is needed in Europe. We will include about 250,000 end stage renal disease patients on renal replacement therapy starting between 2002 and 2015 from the participating national and regional renal registries in Europe. To our knowledge this will be the first study to determine the trends in excess renal replacement therapy-related mortality risk in the European adult population.

Latest approval date

28/03/2019

Safe Data

Dataset(s) name