London School of Hygiene & Tropical Medicine

ILD130

Studies from around the world have suggested that people who developed COVID-19 infection are at increased risk of long-term complications such as heart attack, stroke, kidney failure, blood clots and deterioration in mental health. We know that patients with pre-existing chronic kidney disease (CKD) are at higher risk of severe COVID-19 infection and have therefore been considered a clinically vulnerable group during the pandemic. We do not know the extent of the risk of long-term medical and psychological complications in this patient group. Patients who have been involved in steering our research have consistently emphasised the importance of better understanding these long-term complications. This study will be carried out using patients’ GP records linked to hospital records and UKRR data on the OpenSAFELY platform. We will compare people with CKD who survived COVID-19 infection, with people with CKD before the pandemic, and people without COVID-19 infection during the pandemic. We will look at a range of outcomes including death, kidney failure, heart attacks, stroke, blood clots, mental health outcomes and hospital admissions. This study will help us better understand longer-term complications of COVID-19 infection in people with pre-existing CKD. This can help guide public health interventions and plan renal services.

03/05/2023