University of Leicester

Academic Institute

Mary Barker - Chief Investigator - University of LeicesterFrancesco Zaccardi - Corresponding Applicant - University of LeicesterEdward Gregg - Collaborator - Imperial College LondonJack Sargeant - Collaborator - University of LeicesterKamlesh Khunti - Collaborator - University of LeicesterMelanie Davies - Collaborator - University of Leicester

CPRD855

Type 2 diabetes is a serious condition that causes a person’s blood sugar levels to become too high, often leading to various health complications including damage to the kidney, heart and blood vessels (cardio-renal complications). Traditionally, type 2 diabetes used to occur in older adults; however, in recent years it has increasingly been diagnosed in younger adults. This has been termed early-onset type 2 diabetes, and includes the diagnosis of type 2 diabetes in adults up to 40 or 50 years of age. These younger adults are likely to have other health conditions alongside diabetes, such as obesity, high blood pressure and depression. Studies have also found that when type 2 diabetes is diagnosed at a younger age, the risk of heart and kidney complications and death is higher compared to older adults diagnosed with type 2 diabetes.

Data from the Clinical Practice Research Datalink (CPRD, GOLD and Aurum), linked to Hospital Episode Statistics (HES) and Office for National Statistics (ONS) data, will be used to investigate the following:

23/02/2021

Release