University of Cambridge,University of Bristol

Academic Institute

No

CCU076

COVID-19 infection may become an annual winter virus and follow a clear seasonal pattern, like influenza. Environmental factors, such as extremes in temperature and pollution, could make it easier for the COVID-19 infection to increase the chances of getting a severe case of the virus. This has consequences for cardiovascular risk, as both COVID-19 infection and such environmental factors are known to increase the occurrence of cardiovascular events. However, no study has yet examined the combined effect of both COVID-19 infection and air temperature/pollution on cardiovascular risk. Our research aims to quantify how environmental factors, specifically air temperature and pollution levels, interact with COVID-19 and affect cardiovascular outcomes like heart attacks and strokes. We will also examine whether this interaction is higher in individuals with pre-existing heart conditions.

The findings from our research will offer valuable insights for the public, policy makers and healthcare providers. It will help identify who is at greatest risk of severe cardiovascular outcomes due to environmental factors and COVID-19 infection. This information can help us take specific actions to prevent problems. By helping to identify those at highest risk, our results will support more informed decision-making and inform planning and resource allocation for healthcare services. Global climate change underlines the importance of such research. Visit the BHF Data Science Centre website for more detailed information about project outputs. https://bhfdatasciencecentre.org/projects/ccu076/

This project used the following datasets within the Trusted Research Environment for CVD-COVID-UK / COVID-IMPACT: - Sentinel Stroke National Audit Programme Clinical Dataset - Secondary Uses Services Payment By Results - Covid-19 Second Generation Surveillance System - Hospital Episode Statistics Outpatients - Covid-19 UK Non-hospital Antibody Testing Results - Hospital Episode Statistics Accident and Emergency - Covid-19 UK Non-hospital Antigen Testing Results - Medicines dispensed in Primary Care (NHSBSA data) - COVID-19 Vaccination Status - COVID-19 Vaccination Adverse Reaction - GPES Data for Pandemic Planning and Research (COVID-19) - Hospital Episode Statistics Admitted Patient Care - Civil Registration - Deaths - Hospital Episode Statistics Critical Care - COVID-19 SARI-Watch (formerly CHESS)

20/11/2023

De-Personalised

TRE