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CCU082: Pulmonary arterial hypertension in repaired congenital heart disease: impact of the COVID-19 pandemic on prevalence, late diagnosis and outcomes

Safe People

Organisation name

Imperial College London

Organisation sector

3

Applicant name(s)

Andrew Constantine

Funders/ Sponsors

Safe Projects

Project ID

CCU082

Lay summary

Pulmonary arterial hypertension (PAH) is a serious condition that often affects people born with heart defects (congenital heart disease, CHD), even after surgery to repair their heart problem. This condition can make it hard for patients to breathe and do physical activities, and it can happen even when heart surgery has been successful. With the recent COVID-19 pandemic, there is concern that more people may be facing this issue, and it might be harder to diagnose and treat them in time, putting them at risk of complications. Our research aims to dig deeper into how the COVID-19 pandemic has influenced the number of people developing PAH after their CHD is repaired, how quickly they are being diagnosed, and what their outcomes are. By studying data from the National Congenital Heart Disease Audit and other health records, we hope to understand the true scale of this problem and find better ways to manage it. This is especially important now, as the pandemic might have made things worse for these patients.

Public benefit statement

The findings from our study could lead to big improvements in how we look after people with PAH, particularly those who have had heart surgery. It could help doctors spot the condition earlier, improve treatments, and potentially save lives. This research might also inform health policies and practices, ensuring that the NHS can provide the best care for these patients, even in challenging times like a pandemic.

Other approval committees

Project start date

03/05/2024

Project end date

03/05/2025

Latest approval date

09/06/2024

Safe Data

Dataset(s) name

GPES Data for Pandemic Planning and Research (COVID-19)

Hospital Episode Statistics Admitted Patient Care

Hospital Episode Statistics Outpatients

Emergency Care Data Set (ECDS)

Civil Registration - Deaths

Trusted Research Environments for CVD-COVID-UK / COVID-IMPACT

Data sensitivity level

De-Personalised

Release/Access date

09/06/2024

Safe Setting

Access type

TRE

Safe Outputs

Link to research outputs