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CCU093: Understanding the relationship between diabetes and the development of multiple long-term conditions, during and after the COVID-19 pandemic
Safe People
Organisation name
University of Cambridge
Organisation sector
3
Applicant name(s)
Genevieve Cezard
Funders/ Sponsors
Safe Projects
Project ID
CCU093
Lay summary
Diabetes (a condition where blood sugar level is too high) is associated with key complications such as cardiovascular, kidney, eye and foot conditions. However, people with diabetes may also be more likely to develop other conditions not necessarily flagged as key complications. The landscape of which conditions matter for people with diabetes has changed: • Better prevention and diabetes management in recent years has led to a decline in cardiovascular complications in people with diabetes. • Other conditions not considered as diabetes complications have become more prominent in people with diabetes (e.g. cancer is now the leading cause of death in people with diabetes in England). • The COVID-19 pandemic changed how likely diseases are to develop (e.g. higher risk of cardiovascular disease following COVID-19). Therefore, the conditions that people with diabetes live with and develop after their diabetes diagnosis, warrants further investigation using contemporary data to better tailor care and prevention. This project aims to re-evaluate the relationship between diabetes and the development of multiple long-term conditions, including cardiovascular diseases, cancer and other conditions, during and after the COVID-19 pandemic (from 2020 onwards) to help guide care pathways for people developing diabetes today. The project will use linked electronic health records from the whole populations of England, Scotland and Wales and explore how health inequalities may impact the conditions that people develop after a new diabetes diagnosis.
Public benefit statement
Findings will inform UK-wide and nation-specific policy and guidance (including through existing links with Diabetes UK and national diabetes audits) for the prevention of long-term conditions in people with diabetes. Visit the BHF Data Science Centre website for more detailed information about project outputs. https://bhfdatasciencecentre.org/projects/ccu093/
Technical summary
This project accessed the following datasets within the Trusted Research Environment(s) for CVD-COVID-UK / COVID-IMPACT: - ENGLAND: - Civil Registration - Deaths - Covid-19 Second Generation Surveillance System - Covid-19 UK Non-hospital Antigen Testing Results - COVID-19 Vaccination Status - Emergency Care Data Set (ECDS) - GPES Data for Pandemic Planning and Research (COVID-19) - Hospital Episode Statistics Accident and Emergency - Hospital Episode Statistics Admitted Patient Care - Hospital Episode Statistics Outpatients - Medicines dispensed in Primary Care (NHSBSA data) - Mental Health Services Data Set - MSDS (Maternity Services Data Set) - NICOR – MINAP: Myocardial Ischaemia National Audit Project - NICOR – NACRM: National Audit of Cardiac Rhythm Management - NICOR – NACSA: National Adult Cardiac Surgery Audit - NICOR – NCHDA: National Congenital Heart Disease Audit - NICOR – NHFA: National Heart Failure Audit - NICOR – PCI: Percutaneous Coronary Interventions - NICOR – TAVI: Transcatheter Aortic Valve Implantation - Secondary Care Prescribed Medicines (EPMA) - Sentinel Stroke National Audit Programme Clinical Dataset
Other approval committees
Project start date
03/08/2024
Project end date
02/04/2028
Latest approval date
22/12/2024
Safe Data
Dataset(s) name
Data sensitivity level
De-Personalised
Release/Access date
22/12/2024
Safe Setting
Access type
TRE