HDR Gateway logo
HDR Gateway logo

Bookmarks

CCU094: Identifying preventative opportunities for coronary heart disease and stroke in multi-ethnic patients with non-cardiovascular conditions including COVID-19

Safe People

Organisation name

University of Cambridge

Organisation sector

3

Applicant name(s)

Elias Allara

Funders/ Sponsors

Safe Projects

Project ID

CCU094

Lay summary

Coronary heart disease and stroke are the main cause of death and disability in the world. Some patients with coronary heart disease and stroke have other illnesses that do not primarily involve the heart and vessels, such as pancreatic disorders, kidney diseases and COVID-19 (‘non-cardiovascular diseases’). While researchers have already found links between some non-cardiovascular diseases (for example, diabetes) and coronary heart disease and stroke, we currently do not know much about the links with most other non-cardiovascular diseases. This uncertainty is especially pronounced in minority ethnic groups, which may lead to disparities in the ways people are treated (‘inequalities’). We aim to improve our understanding on the links between non-cardiovascular conditions, including COVID-19, and coronary heart disease / stroke. We plan to do this by studying large numbers of people from different ethnic groups, using mathematical methods that can help find links between the diseases.

Public benefit statement

We expect to discover new and reliable associations between non-cardiovascular and either coronary heart disease or stroke. This work has the potential 1) to help people who have non-cardiovascular diseases avoid heart problems in the future, easing the pressure on the NHS, and 2) to reduce health differences across minority ethnic groups, contributing to a more equitable society.

Other approval committees

Project start date

03/11/2024

Project end date

02/04/2028

Latest approval date

22/12/2024

Safe Data

Dataset(s) name

GPES Data for Pandemic Planning and Research (COVID-19)

Hospital Episode Statistics Admitted Patient Care

Hospital Episode Statistics Critical Care

Hospital Episode Statistics Outpatients

Hospital Episode Statistics Accident and Emergency

Covid-19 Second Generation Surveillance System

Covid-19 UK Non-hospital Antigen Testing Results

Civil Registration - Deaths

Medicines dispensed in Primary Care (NHSBSA data)

Trusted Research Environments for CVD-COVID-UK / COVID-IMPACT

Data sensitivity level

De-Personalised

Release/Access date

22/12/2024

Safe Setting

Access type

TRE

Safe Outputs

Link to research outputs