Queen Mary University of London

3

OFHS240205

This study aims to look at how heart diseases, such as high blood pressure, heart attacks, heart failure, and stroke, develop. We want to better understand what causes these diseases so we can find new ways to prevent, diagnose, and treat them. The research will focus on two main questions: 1. How does lifestyle, like diet and exercise, and other health factors, like smoking or diseases of the immune system, affect the risk of developing heart diseases? 2. Are there differences in the genetic code (DNA) of people with heart diseases, and how do those differences link to lifestyle and health? By answering these questions, we aim to uncover new ways to prevent heart disease and develop better treatments that work for more people. This research seeks to improve our understanding of how heart diseases develop in a large and diverse group of people. It will investigate what causes the heart and blood vessels to stop working properly. The study will focus on both well-known risk factors, such as smoking and exercise, and newer ones, such as diseases of the immune system. By exploring lifestyle and health risk factors we will identify patterns and trends that help explain why some people develop heart diseases while others do not. We also want to study how differences in people’s genetic code influence the development of heart diseases and whether these differences are connected to lifestyle and health risk factors. Some genes may affect more than one heart disease. By finding these genes, we hope to better understand which of them are most important and use that information to identify more effective medicines. By studying lifestyle, health, and genetic risk factors for heart diseases, this research will support the development of new medicines and improve early diagnosis.

This research will help to improve how heart diseases are prevented, diagnosed, and treated. By identifying lifestyle and health risk factors for heart diseases, it will be possible to spot people who are more likely to develop them and take action earlier. Early diagnosis is crucial because it allows for more effective prevention and treatment. We will also study how differences in people’s genetic code affects the development of heart diseases and whether these changes are linked to lifestyle and health risk factors. Understanding how genes contribute to heart diseases will help us learn more about how these conditions develop. From this research we may find new medicines, giving doctors more treatment options that can be tailored to each person’s needs. Overall, this study will help people live longer, healthier lives by improving diagnosis and advancing the treatment options for heart diseases.

Public Health Research

21/03/2025

25/01/2025

TRE