University of Leeds

Academic Institute

Chris Gale - Chief Investigator - University of LeedsKazuhiro Nakao - Corresponding Applicant - University of LeedsJianhua Wu - Collaborator - University of LeedsRamesh Nadarajah - Collaborator - University of LeedsYoko Nakao - Collaborator - University of Leeds

CPRD251

Heart failure (HF) is a disease that develops secondary to multiple underlying diseases that gradually worsens over time. Treatment of underlying disorders is expected to reduce the progression or delay the onset of HF. The diagnostic and treatment processes recommended by current guidelines for HF are expected to improve symptoms, delay disease progression, and improve the prognosis in patients with HF.

To prevent or delay the development of Heart Failure (HF), it is essential to understand the trajectory of HF and provide appropriate interventions at each step to slow progression. However, current treatment for HF is inadequate, and it is unclear whether treating the patient’s HF is sufficient. Hence, the association between variabilities in treatment and patient outcome must be further studied. Moreover, limited information is available for predicting the development of new-onset HF in patients undergoing treatment for underlying diseases, and the effectiveness of treatment of HF-associated comorbidities in clinical practice is unclear.

06/05/2021

Release