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The impact of learning disabilities on control of type 2 diabetes risk factors and outcomes in UK primary care

Safe People

Organisation name

London School of Hygiene and Tropical Medicine

Organisation sector

Academic Institute

Applicant name(s)

Rohini Mathur - Chief Investigator - London School of Hygiene & Tropical Medicine ( LSHTM )Rohini Mathur - Corresponding Applicant - London School of Hygiene & Tropical Medicine ( LSHTM )Archie Wing - Collaborator - London School of Hygiene & Tropical Medicine ( LSHTM )

Safe Projects

Project ID

CPRD36

Lay summary

People with learning disabilities have higher overall levels of chronic disease and die at younger ages than the general population. There is also a higher prevalence of type 2 diabetes mellitus (T2DM) in those with learning disabilities, which is thought to be related to higher levels of obesity, lack of physical activity, lack of access to primary care and dependency on a caregiver. This project will investigate whether the control of diabetes risk factors and risk of major outcomes such as cardiovascular disease, blindness and death differs between those with and without learning disabilities. This will afford us insight into whether people with learning disabilities have worse outcomes than people without learning disabilities and what factors might be associated with these outcomes.

Technical summary

People with learning disabilities (LDs) experience higher rates of mortality, chronic disease, and Type 2 Diabetes (T2DM). There is little evidence exploring the impacts of LDs on control of diabetes-related risk factors and outcomes such as cardiovascular and microvascular disease. It is hypothesised that later diagnosis and poor glycaemic control contribute to worse outcomes, but the extent of these contributions is unknown. The aim of this study is to assess the impact of LDs on the control of cardiometabolic risk factors and clinical outcomes amongst people with T2DM.

Latest approval date

24/05/2021

Safe Data

Dataset(s) name

ONS Death Registration Data

Patient Level Index of Multiple Deprivation

Practice Level Index of Multiple Deprivation

Safe Setting

Access type

Release