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Real-World Effectiveness of Denosumab in Prevention of Fracture among Postmenopausal Osteoporotic Women with FREEDOM Baseline Characteristics

Safe People

Organisation name

University of Oxford

Organisation sector

Academic Institute

Applicant name(s)

Daniel Prieto-Alhambra - Chief Investigator - University of OxfordVictoria Y Strauss - Corresponding Applicant - University of OxfordAnnika Jodicke - Collaborator - University of OxfordAntonella Delmestri - Collaborator - University of OxfordEng Hooi Tan - Collaborator - University of OxfordJoe Maskell - Collaborator - Amgen Ltd

Safe Projects

Project ID

CPRD30

Lay summary

BACKGROUND: A clinical trial, entitled 'FREEDOM', showed that denosumab, a new anti-osteoporosis drug, was efficient in reducing the risk of having a fracture in postmenopausal women suffering from osteoporosis.

Technical summary

OBJECTIVES:

Latest approval date

20/05/2021

Safe Data

Dataset(s) name

HES Admitted Patient Care

ONS Death Registration Data

Patient Level Index of Multiple Deprivation

Safe Setting

Access type

Release