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A comparison of clinical outcomes, health care resource utilisation and costs for patients with chronic lower limb ulcers including diabetic and venous ulcers when prescribed Prontosan (including solution and gel) and saline solution in England
Safe People
Organisation name
Health IQ
Organisation sector
Commercial
Applicant name(s)
Jay Were - Chief Investigator - Health iQJay Were - Corresponding Applicant - Health iQArchie Farrer - Collaborator - Health iQGulsah Akin Unal - Collaborator - Health iQJudith Ruzangi - Collaborator - Health iQMico Hamlyn - Collaborator - Health iQShea O'Connell - Collaborator - Health iQ
Safe Projects
Project ID
CPRD248
Lay summary
Chronic lower limb ulcer (CLLU) is a chronic wound of the leg that shows no tendency to heal after 3 months of appropriate treatment or is still not fully healed at 12 months.
Technical summary
Chronic lower limb ulcers/wounds (CLLU) including diabetic and venous foot ulcers account for a substantial health burden nationally, with an estimated cost representing a total of 2% expenditure of the NHS. This cost burden includes primary care, secondary care stays, surgeries and prescriptions. Traditionally, saline or tap water has been used to clean ulcers prior to applying dressings. Alternatives to saline or tap water include propylbetaine-polihexanide solution (Prontosan™) a wound cleansing agent used to prevent and remove biofilms.
Latest approval date
23/04/2021
Safe Data
Dataset(s) name
HES Accident and Emergency
HES Admitted Patient Care
HES Outpatient
ONS Death Registration Data
Patient Level Index of Multiple Deprivation
Safe Setting
Access type
Release