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A comparison of clinical outcomes, health care resource utilisation and costs for patients with chronic lower limb ulcers including diabetic and venous ulcers when prescribed Prontosan (including solution and gel) and saline solution in England

Safe People

Organisation name

Health IQ

Organisation sector

Commercial

Applicant name(s)

Jay Were - Chief Investigator - Health iQJay Were - Corresponding Applicant - Health iQArchie Farrer - Collaborator - Health iQGulsah Akin Unal - Collaborator - Health iQJudith Ruzangi - Collaborator - Health iQMico Hamlyn - Collaborator - Health iQShea O'Connell - Collaborator - Health iQ

Safe Projects

Project ID

CPRD248

Lay summary

Chronic lower limb ulcer (CLLU) is a chronic wound of the leg that shows no tendency to heal after 3 months of appropriate treatment or is still not fully healed at 12 months.

Technical summary

Chronic lower limb ulcers/wounds (CLLU) including diabetic and venous foot ulcers account for a substantial health burden nationally, with an estimated cost representing a total of 2% expenditure of the NHS. This cost burden includes primary care, secondary care stays, surgeries and prescriptions. Traditionally, saline or tap water has been used to clean ulcers prior to applying dressings. Alternatives to saline or tap water include propylbetaine-polihexanide solution (Prontosan™) a wound cleansing agent used to prevent and remove biofilms.

Latest approval date

23/04/2021

Safe Data

Dataset(s) name

HES Accident and Emergency

HES Admitted Patient Care

HES Outpatient

ONS Death Registration Data

Patient Level Index of Multiple Deprivation

Safe Setting

Access type

Release