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Can we use routinely collected primary care medical records to assess and explain variations in major lower extremity amputation rates across the England?

Safe People

Organisation name

University of Leicester

Organisation sector

Academic Institute

Applicant name(s)

Laura Gray - Chief Investigator - University of Leicester - Corresponding Applicant -Andrew Nickinson - Collaborator - University of LeicesterClare Gillies - Collaborator - University of LeicesterJohn Houghton - Collaborator - University of LeicesterKamlesh Khunti - Collaborator - University of LeicesterRob Sayers - Collaborator - University of LeicesterTanya Payne - Collaborator - University of Leicester

Safe Projects

Project ID

CPRD685

Lay summary

Individuals with poor circulation to their lower limbs (known as ‘chronic limb-threatening ischemia’) or diabetes mellitus can end up needing to have part, or even all, of their leg amputated. Having an amputation can have a devastating impact on a person’s quality of life and can be a life changing event. Despite this, there is uncertainty over the number of amputation procedures performed in the England.

Technical summary

This study comprises two work packages which are outlined below.

Latest approval date

17/03/2021

Safe Data

Dataset(s) name

2011 Rural-Urban Classification at LSOA level

HES Admitted Patient Care

ONS Death Registration Data

Patient Level Index of Multiple Deprivation

Safe Setting

Access type

Release