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Burden of Disease and Treatment Patterns for Patients with Hip and Knee Osteoarthritis in the United Kingdom

Safe People

Organisation name

Evidera

Organisation sector

Commercial

Applicant name(s)

Javier Cid - Chief Investigator - EvideraIncAlison Booth - Corresponding Applicant - EvideraIncMickael Hiligsmann - Collaborator - Maastricht UniversityMireia Raluy Callado - Collaborator - EvideraIncNoami Berfeld - Collaborator - EvideraIncPhilip Conaghan - Collaborator - University of LeedsRavi Iyer - Collaborator - Teva Pharmaceuticals LtdRobert Donaldson - Collaborator - EvideraIncSangtaeck Lim - Collaborator - Teva Pharmaceuticals LtdTahir Saleem - Collaborator - Teva Pharmaceuticals Ltd

Safe Projects

Project ID

CPRD697

Lay summary

Osteoarthritis is a painful disease of the knees, hips and other joints in the body. About 10% of UK adults have osteoarthritis, which often gets worse over time. We don’t yet know how to stop osteoarthritis getting worse. So, we treat it by replacing the affected joint or by using medicines to reduce pain. There is not a lot of published information available to help understand the economic impacts to healthcare systems that osteoarthritis may have.

Technical summary

Osteoarthritis (OA) is a degenerative joint disease affecting the cartilage and surrounding tissues. In the United Kingdom (UK), approximately 10% of adults have symptomatic and clinically diagnosed OA, with knee OA being the most common. There are no current treatments available to stop or slow OA progression, hence pharmacological management of OA patients focuses on symptom management (i.e. analgesics for pain), with minimal impact on the underlying disease. Published data on estimated direct and indirect costs of OA in the UK are limited, suggesting that more research into this area is imperative to understand burden of OA in the UK

Latest approval date

18/03/2021

Safe Data

Dataset(s) name

HES Accident and Emergency

HES Admitted Patient Care

HES Outpatient

Patient Level Index of Multiple Deprivation

Safe Setting

Access type

Release