Bookmarks
ID 308: The comparative value of RWE as generated from the Systemic Anti Cancer Treatment database or trial evidence - approved subject to amending the form to reflect committee members' comments
Safe People
Organisation name
Department of Surgery & Cancer at Imperial College London
Applicant name(s)
Funders/ Sponsors
Safe Projects
Project ID
ID 308
Lay summary
This project aims to review clinical trials data for select drugs that gained approval through the process above using SACT data, by comparing RWD derived from Discover
Public benefit statement
This study presents an opportunity to compare two large datasets, one focusing on anti-cancer treatments for patients across England (called SACT) and another (called Discover) based on de-identified data for patients registered with a GP in North West London. This project will compare these data to inform on how SACT-derived data is used by NICE to inform on recommendations for innovative anti-cancer medications. Potential outcomes include highlighting strengths, weakness, and limitations of the use of one database for technology appraisals, whilst recommendations for improved recommendations using RWD are also targeted.
Other approval committees
Latest approval date
16/02/2023
Safe Data
Dataset(s) name
Safe Setting
Access type
TRE