Clinical Practice Research Datalink (CPRD)

Independent Sector Organisation

Eleanor Yelland - Chief Investigator - CPRDEleanor Yelland - Corresponding Applicant - CPRDRachael Williams - Collaborator - CPRDSusan Hodgson - Collaborator - CPRD

CPRD852

CPRD supports public health research through the provision of de-identified primary care data and a number of linkages to other routinely collected health data sources. A new linkage to the Public Health England (PHE) Second Generation Surveillance System (SGSS) SARS-CoV-2 positive test data has recently been established (COVID-19 is the disease name and SARS-CoV-2 is the virus name). This works aims to describe the recording of COVID-19 diagnosis and test results across the CPRD primary care data and SGSS test data and assess how well these agree. The groups of patients with a diagnosis or positive test result in the different databases will be described by age, gender, region, ethnicity and an indicator of how deprived the area is that the patient lives in. We will establish how many of the COVID-19 records in primary care are confirmed in the linked test data as well as how many of the patients with a positive PHE test record also have that information recorded in their primary care data.

CPRD provide de-identified primary care data for public health research. In light of the COVID-19 global pandemic, linkage to the Public Health England (PHE) Second Generation Surveillance System (SGSS) SARS-CoV-2 positive virology pillar 1 test data was established. The added value of these data is currently poorly understood. We will establish the agreement of primary care recording around COVID-19 and the linked SGSS SARS-CoV-2 positive test data. This will assess the added value of the SGSS-linkage and contribute to our understanding of how well COVID-19 diagnoses are being recorded in primary care data. This knowledge is crucial to support research into COVID-19 using these data sources, which in turn can inform our understanding of the disease and inform patient care and public health policy.

11/02/2021

Release