University of East Anglia

Academic Institute

Kathryn Richardson - Chief Investigator - University of East AngliaKathryn Richardson - Corresponding Applicant - University of East AngliaChris Fox - Collaborator - University of East AngliaDuncan Edwards - Collaborator - University of CambridgeIrene Petersen - Collaborator - University College London ( UCL )Jalesh Panicker - Collaborator - National Hospital for Neurology and NeurosurgeryKatharina Mattishent - Collaborator - University of East AngliaLouise Robinson - Collaborator - Newcastle UniversityNicholas Steel - Collaborator - University of East AngliaStuart Irving - Collaborator - Norfolk and Norwich University HospitalsYoon Loke - Collaborator - University of East Anglia

CPRD874

Overactive bladder is increasingly common as people age and can severely affect quality of life. It is often treated with medications called ‘anticholinergics’ or ‘antimuscarinics’, but some studies have associated these with memory problems and a higher risk dementia if used for a long time.

Previous studies suggest that long-term overactive bladder (OAB) anticholinergic use may increase dementia risk, however studies suffer from residual confounding and protopathic bias. This topic requires more detailed investigation and as identified by the National Institute of Health and Care Excellence.

02/02/2021

Release