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Respiratory tract infections in ICU - The burden, management strategies adopted and outcomes of severe respiratory tract infections in intensive care units- Wessex clinical research collaboration from Wessex Intensive Care Innovation and Research Network (WICIR)

Safe People

Organisation name

University Hospital Southampton NHS Foundation Trust

Applicant name(s)

Funders/ Sponsors

Safe Projects

Project ID

SDE_WXS_PROJ_81

Lay summary

Serious lung infections are a common problem. This research project will study how people with serious lung infections are cared for in intensive care units and what happens to them during and after their treatment. The regional study will focus on all types of severe respiratory tract infections treated in the ICUs across the Wessex region. We will use the information that is already available from different data bases from various hospitals to combine the data to provide a detailed information on the severity of lung infections, the treatment they received (such as ventilators or medicines to support their heart or kidneys) and whether they survived their stay in ICU or hospital. This will help to understand the burden of these infections locally and how care varies between hospitals. We will collect all available data to assess how patient can be best managed with severe respiratory tract infections and how this could be improved in the future.

Public benefit statement

The project has several important benefits for patients and public. First, it will help identify how many patients are affected by serious respiratory infections and how are they treated (this is currently unknown). Second, it will help NHS services plan better for the future, especially during winter or times of high demand or during pandemics. Third, it will highlight any variations in care between centres that could be improved. Finally, the results will help researchers design better clinical trials to test new treatments by showing where the needs are greatest and which patients are at highest risk. We will not collect any new information from patients and no individuals will be identified. The data is already available in clinical settings. We will collect these data and the findings will be shared with doctors, nurses, NHS leaders and the public to support better care for people with serious lung infections.

Other approval committees

Latest approval date

26/09/2025

Safe Data

Dataset(s) name

Wessex ICU data

Safe Setting

Access type

TRE

Safe Outputs

Link to research outputs