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CCU107: An intersectionality approach to evaluate the variation of statins and anticoagulants prescriptions among stroke survivors before and during COVID-19

Safe People

Organisation name

King's College London

Organisation sector

Academic Institute

Applicant name(s)

Alejandro Gonzalez-Aquines

Funders/ Sponsors

Safe Projects

Project ID

CCU107

Lay summary

One way of reducing the chances of a second stroke is through medication. For example, blood thinners (anticoagulants) and medication to lower cholesterol levels (statins). But about one out of three stroke survivors do not get these medications, with some population groups (i.e., elderly people, people from low socioeconomic backgrounds) being less likely to receive them. The COVID-19 pandemic revealed that the inequality in prescription practices was exacerbated, increasing the health inequalities gap. While it is widely acknowledged that prescription practices are influenced by the person’s characteristics (i.e., age, gender, and socioeconomic status), new research shows that the chances of not receiving medication are higher when those characteristics are combined. For example, a high-income 55-year-old White man might have a higher chance of receiving medication compared to a 75-year-old South Asian woman. This approach is called intersectionality, a critical theory that helps understand how the combination of a person’s identities overlaps to create unique experiences of privilege or discrimination. This research will study the differences in the prescription of medications to prevent a second stroke before and during the COVID-19 pandemic. Understanding who is less likely to receive medication to prevent a second stroke is important to develop strategies to ensure everyone receives the care they need.

Public benefit statement

The findings will help to develop priority areas to enhance prescription practices in stroke secondary prevention and report the impact health emergencies like COVID-19 can have on prescription practices. The results of this work will have the greatest impact on stroke survivors who are not receiving medication to prevent a second stroke. In the long term, improving prescription practices will be felt by the NHS and carers by reducing recurrent strokes.

Technical summary

This project accessed the following datasets within the Trusted Research Environment(s) for CVD-COVID-UK / COVID-IMPACT: - ENGLAND: - GPES Data for Pandemic Planning and Research (COVID-19) - Hospital Episode Statistics Admitted Patient Care - Medicines dispensed in Primary Care (NHSBSA data) - Secondary Care Prescribed Medicines (EPMA)

Other approval committees

Project start date

15/10/2025

Project end date

15/10/2026

Latest approval date

18/12/2025

Safe Data

Dataset(s) name

Data sensitivity level

De-Personalised

Release/Access date

18/12/2025

Safe Setting

Access type

TRE

Safe Outputs

Link to research outputs