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National Core Study - Data and Connectivity: COVID-19 Vaccines Pharmacovigilance (DaC-VaP)
Safe People
Organisation name
Queen's University Belfast
Organisation sector
Academic Institute
Applicant name(s)
Dr Declan Bradley
Funders/ Sponsors
Queen's University BelfastHealth Data Research UKwider NCS team
Safe Projects
Project ID
36367500000000000, E064
Lay summary
The aim of this study is to assess the safety, effectiveness and uptake of the currently licenced COVID-19 vaccines (Pfizer-BioNTech, Oxford-AstraZeneca and Moderna) in the UK. To do this, we will use anonymised individual level data routinely collected at primary, secondary, linked with mortality, laboratory and vaccination data across the UK. Unique national datasets will be developed and hosted within a Trusted Research Environment (TRE) in each UK nation with standardised individual-level analyses run across datasets. Pooled estimates across the UK national will also be provided. Specifically, our objectives are to: a) assess any vaccine related adverse events; b) assess vaccine effectiveness (VE) including household transmission; and c) measure variation in vaccine uptake
Public benefit statement
The findings from this study are anticipated to provide important public health information on uptake characteristics and the safety and effectiveness of the vaccination programme in the NI population.
Latest approval date
18/03/2021
Safe Data
Dataset(s) name
National Health Application and Infrastructure Services (NHAIS)
GRO Mortaltiy Data
VMS
PAS
Data sensitivity level
Anonymous
Legal basis for provision of data under Article 6
Not applicable
Common Law Duty of Confidentiality
Not applicable
National data opt-out applied?
Not applicable
Request frequency
Recurring
Safe Setting
Access type
TRE