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Immuno-Metabolic Predictors of Anhedonic Depression and Treatment Response The IMPACT Programme

Safe People

Organisation name

University of Bristol

Organisation sector

Academic Institute

Applicant name(s)

Golam Khandaker

Safe Projects

Project ID

B3877

Lay summary

The current work looks to examine the underpinnings of anhedonic depression - i.e. depression associated with an inability to feel pleasure. This is an important group and little is know about the factors that characterise and are important for this outcome. The work will use detailed questionnaires to examine the likely presence or absence of this presentation in ALSPAC participants and there will be extremely detailed followup of a sub-set of participants likely to have this condition. This work will be in parallel with that in a study called NESDA in The Netherlands - providing important replication and sample size.

Public benefit statement

Discovery science re. this presentation with likely information re. augmented therapeutic strategies.

Latest approval date

16/09/2021