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MR-PREG Consortium 26-07-2021
Safe People
Organisation name
University of Bristol
Organisation sector
Academic Institute
Applicant name(s)
Amy Taylor
Carolina Borges
Deborah Lawlor
Alice Carter
Marwa Al Arab
Nancy Mcbride
Ana Luiza Soares
Qian Yang
Alba Fernandez-Sanles
Fanny Kilpi
Safe Projects
Project ID
B3844
Lay summary
ALSPAC contributes to a group of studies called MR-PREG which aims to investigate the impact of maternal exposures during pregnancy (such as BMI, smoking, blood pressure) on pregnancy complications, perinatal outcomes and later offspring outcomes. MR-PREG uses genetic data to explore whether associations between maternal exposures and these outcomes are likely to be causal.
Public benefit statement
There are already several papers in progress from the initial MR-PREG analyses. This work will be important for identifying the impact of maternal exposures during pregnancy and possible targets for intervention (e.g. healthy BMI ranges for pregnant women to prevent preterm birth).
Latest approval date
20/09/2021