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MR-PREG Consortium 26-07-2021
Safe People
University of Bristol
Academic Institute
Amy TaylorCarolina BorgesDeborah LawlorAlice CarterMarwa Al ArabNancy McbrideAna Luiza SoaresQian YangAlba Fernandez-SanlesFanny Kilpi
Safe Projects
B3844
ALSPAC contributes to a group of studies called MR-PREG which aims to investigate the impact of maternal exposures during pregnancy (such as BMI, smoking, blood pressure) on pregnancy complications, perinatal outcomes and later offspring outcomes. MR-PREG uses genetic data to explore whether associations between maternal exposures and these outcomes are likely to be causal.
There are already several papers in progress from the initial MR-PREG analyses. This work will be important for identifying the impact of maternal exposures during pregnancy and possible targets for intervention (e.g. healthy BMI ranges for pregnant women to prevent preterm birth).
20/09/2021