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Mother and Infant Research Electronic Data Analysis

Safe People

Organisation name

The MIREDA Partnership

Organisation sector

Academic Institute

Applicant name(s)

Funders/ Sponsors

Medical Research Council (MR/X02055X/1)

Safe Projects

Project ID

MRX02055X1

Lay summary

The MIREDA partnership harmonises five UK birth cohorts into the OMOP Common Data Model. This creates a resource representing 17.5 million births to improve health outcomes for mothers and infants.

Public benefit statement

The MIREDA partnership harmonises five UK electronic birth cohorts (Born in Bradford, Born in South London, Born in Scotland, Born in Wales, and CPRD England) into the OMOP Common Data Model. This creates a population-scale resource representing 17.5 million births, enabling secure, federated research to improve health outcomes for mothers and infants without moving individual-level data.

Request category type

Public Health Research

Technical summary

Implementation of a federated analysis infrastructure using the OMOP Common Data Model v5.4. Data from five cohorts were harmonised locally within separate TREs (SAIL, BEAR, etc.) using CaRROT tools and WhiteRabbit metadata scan reports.

Other approval committees

Local TRE Governance (SAIL IGRP etc.)

Project start date

06/01/2023

Project end date

06/01/2026

Latest approval date

06/01/2023

Safe Data

Dataset(s) name

Data sensitivity level

De-Personalised

Legal basis for provision of data under Article 6

(e) processing is necessary for the performance of a task carried out in the public interest or in the exercise of official authority vested in the controller;

Lawful conditions for provision of data under Article 9

(j) processing is necessary for archiving purposes in the public interest, scientific or historical research purposes or statistical purposes in accordance with Article 89(1) based on Union or Member State law which shall be proportionate to the aim pursued, respect the essence of the right to data protection and provide for suitable and specific measures to safeguard the fundamental rights and the interests of the data subject.

Common Law Duty of Confidentiality

Section 251 NHS Act 2006

National data opt-out applied?

Yes

Request frequency

One-off

For linked datasets, specify how the linkage will take place

Reference tables for original identifiers and OMOP identifiers are retained by TREs to link to other non-OMOP datasets.

Description of the confidential data being used

Pseudonymised maternal and infant health records, including demographics, pregnancy characteristics, delivery information, and infant outcomes.

Release/Access date

01/06/2023

Safe Setting

Access type

TRE

Safe Outputs