Bookmarks
Identifying markers for brain signatures of adolescent depression and depression risk
Safe People
Organisation name
University of Edinburgh
Organisation sector
Academic Institute
Applicant name(s)
Heather Whalley
Miss Amelia Edmonson-Stait
Dr Alex Kwong
Safe Projects
Project ID
B3860
Lay summary
We currently have another proposal (B3421) investigating the brain signatures of adolescent depression and depression risk. In order to fully examine this project, we are running some initial analysis to define the most robust markers of depression across adolescence. From preliminary analysis and other research, we have found that trajectories of depressive symptoms may be robust markers for some brain signatures. Additionally, these trajectories could mediate the relationship between early risk factors and later brain signatures. Therefore, we are running additional analysis on the trajectories to validate these findings and we will examine them with the following methods. Please note, we already have access to the data, this is a student project using that data.
Public benefit statement
Shed light on biological mechanisms underpinning depression
Latest approval date
13/09/2021