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Lipid Profile and DNA methylation
Safe People
Organisation name
University of Bristol
Organisation sector
Academic Institute
Applicant name(s)
Giulia MancanoDr Gemma SharpDr Janine F. FelixGiulietta Monasso
Safe Projects
Project ID
B3827
Lay summary
Unfavourable lipid profile (i.e. dyslipidemia) is an established cause of cardiovascular diseases (CVDs). In recent years, several CpGs sites have been found on lipid-related genes or associated with lipid profiles, supporting the hypothesis that DNA methylation (DNAm) could be involved in regulating these genes and their role in lipid-related diseases [1].
Public benefit statement
Build evidence on the link between lipids and DNA methylation and on the mechanistic pathway linking lipids to adverse health outcomes
Latest approval date
12/07/2021