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Polygenic susceptibility in chronic air pollution exposure associated adverse respiratory health in adolescents a meta-analysis
Safe People
Organisation name
University of Bristol
Organisation sector
Academic Institute
Applicant name(s)
Raquel GranellDr Tamara SchikowskiSara KressDr Claudia Wigmann
Safe Projects
Project ID
B3814
Lay summary
Several studies support an association between being exposed to air pollution and having respiratory health problems in adolescence. However, only some of those who are highly exposed to air pollution develop respiratory diseases. Genetics play a role in how an individual respons to air pollution exposure as well as in the probability to develop air pollution induced respiratory health problems. We want to investigate if there is a difference in how air pollution affects our respiratory health, when comparing 'genetic low-risk' and 'genetic high-risk' groups of people.
Latest approval date
21/06/2021