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Common maternal variants and the occurrence of Cleft in their children
Safe People
Organisation name
University of Bristol
Organisation sector
Academic Institute
Applicant name(s)
Garan JonesProfessor Sarah LewisDr. Evangelia StergiakouliDr Gemma C Sharp
Safe Projects
Project ID
B3683
Lay summary
The Cleft Collective Cohort Studies investigates the biological and environmental causes of cleft, the best treatments for cleft and the psychological impact of cleft on those affected and their families. With the help of every cleft team in the UK, up to 3,500 children and their families will be recruited into the study.
Public benefit statement
We hope to find evidence for some of the underlying mechanisms and pathways that contribute to the development of cleft in children and the effects of maternal genetics on development of the foetus.
Latest approval date
03/06/2021