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Prevalence of ideal cardiovascular health in preschoolers early determinants and associations with neurodevelopment

Safe People

Organisation name

INSERM

Organisation sector

Government Agency (Health and Adult Social Care)

Applicant name(s)

HEUDEEMPANA Jean-PhilippeDrTAFFLET MurielMrsCLIMIE RachelDrCHARLES Marie-AlineDr

Safe Projects

Project ID

B3739

Lay summary

In the context of the concept of primordial prevention, a score of ideal cardiovascular health has been defined by the American Heart Association (Lloyd Jones et al. 2010). In adults, a higher score as been associated to a Incident Cardiovascular Events, lower Cognitive Decline and Incident Dementia (van Sloten et al. 2018; Samieri et al. 2018). This score relies on the combination of “ideal” values for 7 metrics from cardiometabolic health and behaviours. Ideal values will be defined as recommended values from previous studies and/or from internal thresholds. The list of the 7 metrics entering the score is as follows: Body mass index, physical activity, healthy diet, smoking, blood pressure, fasting plasma glucose, total cholesterol. Two sub-scores can be computed, one from the behavioural components (BMI, physical activity, diet and smoking), and the other from the clinical and biological components (blood pressure, glucose and cholesterol).

Latest approval date

22/03/2021