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Maternal asthma and offspring methylation EWAS Meta-analysis of PACE cohorts
Safe People
Organisation name
University of Bristol
Organisation sector
Academic Institute
Applicant name(s)
Raquel Granell
Klaus Bønnelykke
Professor
Hanna Elliott
Dr
Safe Projects
Project ID
B3719
Lay summary
Background Asthma is a highly heritable disease with parental asthma being the strongest known risk factor for asthma in the offspring. Maternal asthma is a stronger risk factor than paternal asthma suggesting a role of epigenetic effects. Furthermore, clinical studies have suggested that parental effects might be sex-specific.
Latest approval date
16/02/2021