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Data intensive research using national database: Predictors of adverse outcome in cooled infants with hypoxic-ischaemic encephalopathy (HIE) and perinatal infection
Safe People
Organisation name
University of Bristol
Organisation sector
Academic Institute
Applicant name(s)
Ela Chakkarapani
Funders/ Sponsors
University of Bristol
Safe Projects
Project ID
nnrd34
Lay summary
This study is a collaborative study between researchers in the GW4 (University of Bristol, Cardiff University, Exeter University), University of Dusseldorf and Imperial College led by Dr Ela Chakkarapani at the University of Bristol. The study will use the data of infants who underwent cooling therapy for neonatal encephalopathy held in the National Neonatal Research Database (the NNRD). The team will investigate the effect of pre-sensitisation with infection or culture-positive sepsis on death and adverse outcomes. This will determine the predictors of death and adverse outcomes in cooled infants exposed to infection.
Other approval committees
REC reference: 18/NW/0377
Safe Setting
Access type
Release