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The impact of COVID19 on acute kidney injury (AKI) in the UK -a descriptive analysis from the UKRR

Safe People

Organisation name

UK Renal Registry/London School of Hygeine and Tropical Medicine

Safe Projects

Project ID

ILD96

Lay summary

The COVID19 pandemic started in February 2020. COVID19 is known to cause acute kidney injury (AKI). AKI is a sudden decline in kidney function which is serious and requires prompt treatment. The aim of this study is to carry out an analysis of UKRR AKI-MPI data to describe the impact of the pandemic on the epidemiology (incidence and distribution) of AKI in the UK. We will link data from centres which reported complete AKI alert data between Jan 2020-July 2020, to positive covid test data from Public Health England. We will compare the amount of AKI alerts in these centres with data from 2019 and highlight which of these AKI alerts are for covid positive patients. This will show us the impact of covid-19 on the incidence and distribution of AKI in the UK. The study will also allow us to understand the mortality risk for AKI patients with a positive vs negative covid result. The study will also compare patient features in the 2019 vs 2020 AKI population to highlight changes in care delivery caused by covid-19. This study will clarify the challenges around care delivery for people with AKI during the pandemic and aims to prove that the post-pandemic data is not at all comparable with the pre-pandemic data. As such, this analysis will clarify challenges of using existing indicators in a post COVID world.

Latest approval date

16/03/2021

Safe Data

Dataset(s) name