Uk Renal Registry

ILD98

The UK Renal Registry (UKRR) published research has shown that kidney disease is a recognised risk factor for poor COVID-19 outcomes. In patients that tested positive for Covid-19 up to 30 June 2020, survival at 1 week after date of positive COVID-19 test was 87.5% and 80.0% at 2 weeks. Mortality increased with age and time on dialysis, and there was borderline evidence of Asian ethnicity being associated with higher mortality. Compared to the general population, the relative risk of mortality for in-centre haemodialysis patients with COVID-19 was 45.4 and highest in younger adults. It is important to understand if there is a difference in infection rates and patient features and outcomes in wave 2 of Covid-19 compared to wave 1. This study will use data from Public Health England and the UKRR to analyse all Covid-19 positive patients from the start of the pandemic (March 2020) to the most recent data. Patients that tested positive in wave 1 (March-August 2020) and wave 2 (from September 2020 onwards) will be compared to highlight any differences in patient features and outcomes between wave 1 and wave 2. The results from the wave 1-wave 2 comparison will inform on the suspected difference in patient outcomes between the 2 waves. National data shows some evidence of more severe disease and a higher death rate in wave 2. It would be important to confirm this for Kidney Replacement Therapy patients.

16/03/2021